33 results
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
Causes of Thrombocytopenia ... methotrexate) • Drugs ... anti-HLA antibodies Drugs ... Non-lmmune: • HELLP Syndrome ... #Hematology
Managing warfarin INR

Warfarin dosage must be individualized according to the patient's response to the drug, and
response to the drug ... #management #algorithm ... pharmacology #treatment #medications ... #table #pharmacotherapy ... decisionaid #cardiology #hematology
A toxidrome is a syndrome (set of symptoms) caused by specific medications or toxins.

There are 5
toxidrome is a syndrome ... set of symptoms) caused ... by specific medications ... barbituates, “Z-drugs ... Toxidromes #Comparison #Table
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Drug Induced Liver ... duration), Several medications ... , Hidden OTC and ... for alternative causes ... Diagnosis #Algorithm #hepatology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... ) - HELLP syndrome ... Hemolytic uremic syndrome ... infection) - Drugs ... differential #diagnosis #hematology
Causes of Thrombocytopenia - Differential Diagnosis Framework
Decreased Production:
 - Drugs (chemo, yang, sulfa, acetaminophen, NSAIDs, quinine,
Causes of Thrombocytopenia ... Production: - Drugs ... NSAIDs, quinine, etc ... antiphospholipid syndrome ... Diagnosis #Framework #hematology
Consensus Indications for Irradiated RBC Transfusions:

Cellular blood components are irradiated for the prevention of TA-GVHD. Transfused
Consensus Indications ... disorders (DiGeorge Syndrome ... HLA-selected products (e.g ... #Hematology #BloodBank ... #Management
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
Anti-histone - Drug-induced ... - Vasculitis, e.g ... - Vasculitis, e.g ... diseases #diagnosis #table ... #rheumatology #
Hydroxychloroquine Serum Measurement in SLE
 • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
200ng/mL Best indications ... • Special cases ... (e.g. renal failure ... Measurement #SLE #rheumatology ... levels #lupus #management
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Causes of Anemia ... Blood Smear • Drugs ... Increased Requirement (e.g ... Myelodysplastic Syndromes ... #Hematology