12 results
Thrombotic Microangiopathy - TTP VS HUS

Big picture points : Often hard to differentiate the two entities,
HUGE treatment ... and first-line treatment ... #thrombocytopenia ... Comparison #Diagnosis #Table ... #Hematology
Thrombotic Microangiopathies - Primary Thrombotic Microangiopathy (TMA) - Differential Diagnosis Table

 • Thrombotic Thrombocytopenic Purpura (TTP)
Differential Diagnosis Table ... • Thrombotic Thrombocytopenic ... HUS (aHUS) ... Metabolism-mediated TMA - Coagulation-mediated ... Microangiopathy #TMA #hematology
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
Thrombocytopenia ... Pregnancy - TTP/HUS ... the critically ill ... AFLP #obstetrics #hematology ... #diagnosis #table
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
Causes of Thrombocytopenia ... ITP • SLE • CLL ... Syndrome • TTP/HUS ... Heart Valve) #Thrombocytopenia ... Algorithm #Causes #Hematology
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
Thrombocytopenia ... the critically ill ... presents with coagulation ... Obstetrics #OBGyn #Hematology ... Diagnosis #Comparison #Table
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
intravascular coagulation ... microangiopathy: Thrombotic thrombocytopenic ... uremic syndrome (HUS ... . lupus, CLL, lymphoma ... differential #diagnosis #hematology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
DDX: • TMA’s (HUS ... - MAHA: TTP/HUS ... + Bleeding Treatment ... diagnosis #causes #treatment ... #management #hematology
Thrombotic Microangiopathy - TMAs
1. Not all MAHAs are due to TMAs but (almost) all TMAs cause
Not all MAHAs are ... triad of MAHA + thrombocytopenia ... TTP (atypical HUS ... metabolism and coagulation-mediated ... Microangiopathy #TMAs #hematology
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
blisters containing pus ... and lower jaw Treatment ... antiinflammatory properties e.g ... Tetracyclines etc ... diagnosis #management #Dermatology
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
in recipient (e.g ... haptoglobin, ↑LDH, etc ... purpura & severe thrombocytopenia ... Occurs between 0-6 hrs ... diagnosis #management #hematology