34 results
Acquired von Willebrand Syndrome - Diagnosis and Management
 • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
Acquired von Willebrand ... and Management ... thrombocythemia), Autoimmune disease ... #treatment #hematology ... #differential
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
HELLP - Grafts, Valves ... Drug-associated, PCH ... , Evans Syndrome ... Defects: Sickle cell anemia ... #Diagnosis #hematology
Diagnostic Framework for Anemia (Morphological Approach - MCV)
Low MCV - <80fL - "Microcytic"
 • Iron deficiency
chronic kidney disease ... patients), "Hospital-acquired ... Myelodysplastic syndrome ... morphologic #mcv #differential ... diagnosis #causes #hematology
Pancytopenia - Workup and Differential Diagnosis Algorithm
Consumption Disorders
 1. Autoimmune Mediated Pancytopenia
 2. Splenic Sequestration
Peripheral Destruction
HLH syndrome 5. ... Cytogenetics and FISH • Acquired ... Aplastic Anemia ... Metastatic Disease ... Diagnosis #Algorithm #Hematology
Pancytopenia - Workup and Differential Diagnosis Algorithm
Consumption Disorders
 1. Autoimmune Mediated Pancytopenia
 2. Splenic Sequestration
Peripheral Destruction
HLH syndrome 5 ... Cytogenetics and FISH • Acquired ... Aplastic Anemia ... Metastatic Disease ... Diagnosis #Algorithm #Hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Platelet Count - Differential ... hemolysis, deficiency anemia ... Rebound effect from treatment ... Vasculitides, IBD, Celiac disease ... Kawasaki, Nephrotic syndrome
Autoimmune Hemolytic Anemia (AIHA) Treatment
Warm AIHA:
1) Steroids - 1-2 mg/kg prednisone daily
   • Until
Autoimmune Hemolytic Anemia ... (AIHA) Treatment ... esp if severe disease ... , Splenectomy, MMF ... #management #hematology
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework

LDH is a cytoplasmic enzyme present in tissues throughout
Dehydrogenase (LDH) - Differential ... cell enzymes - Acquired ... - Prosthetic valves ... Myopathies (inherited, acquired ... • Tumor lysis syndrome
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
the secondary or acquired ... with leukopenia, anemia ... Treatment: • Corticosteroids ... #Diagnosis #Management ... #Hematology #Rheumatology
Renal Cell Carcinoma (RCC) - Diagnosis and Management Summary
Clinical features - Classic triad (flank pain, hematuria,
Diagnosis and Management ... Anemia (common) ... Budd Chiari syndrome ... Imaging and Treatment ... #Diagnosis #Management