20 results
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
- Differential ... Injury: • Hepatic ... Venoocclusive disease • Hepatic ... function may be abnormal ... RBC (hemolysis, bleeding
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
HELLP - Grafts, Valves ... Drug-associated, PCH ... Defects, Drugs, Liver ... Blood Smear ↑ abnormal ... #Diagnosis #hematology
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm
Thrombocytopenia - Quantitative Defect
 • Decreased Production
 •
Causes of Bleeding ... / Bruising - Differential ... Destruction • Abnormal ... Iatrogenic) • Liver ... Algorithm #Causes #Hematology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Low Mean Corpuscular Volume (<80
Volume (MCV) - Differential ... Chronic Disease Normal ... 80-100 fL) • Bleeding ... Renal Disease, Liver ... Algorithm #Causes #Hematology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm
Extravascular - Spleen and RES-mediated hemolysis
 -
Intravascular Hemolysis - Differential ... Drug-induced AIHA - Abnormal ... Cold AIHA • PCH ... Prosthetic heart valves ... Algorithm #Causes #Hematology
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
of Hemostasis - Differential ... PT/ABNORMAL PTT ... Acquired: • Heparin ... Bruising #Hemostasis #Differential ... #Diagnosis #Hematology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
Syndrome, Ischemic Liver ... atherosclerotic lesions ... Hyperhomocysteinemia - Heparin-induced ... pathophysiology #hematology ... #differential #
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
dysfunction (25%) • Hepatic ... DIC • Severe Liver ... deficiency) • HIT: Heparin-PF4 ... 100mg/dL) - Heparin ... treatment #management #hematology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
cholestasis → Cirrhosis/Liver ... or higher • Liver ... bile ducts Differential ... malignancies, Hepatic ... diagnosis #workup #hepatology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... hemorrhagic skin lesions ... deficiency • Liver ... #Diagnosis #hematology ... #nonpalpable #dermatology