26 results
Causes of Splenomegaly - Differential Diagnosis Algorithm
Infectious
 • Bacterial
 • Viral (EBV)
 • Parasitic
 • Fungal
Congestive
Differential Diagnosis Algorithm ... • Thrombus (e.g ... Myeloproliferative disorders (eg ... Inflammatory • Systemic Lupus ... #Causes #Hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
(usually IgG) (e.g ... . lupus, CLL, lymphoma ... (usually IgM) (e.g ... deficiencies (e.g ... differential #diagnosis #hematology
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
La) - Sjogren's syndrome ... - Vasculitis, e.g ... - Vasculitis, e.g ... #diagnosis #table ... #rheumatology #
Inflammatory Joint Pain - Differential Diagnosis Algorithm 
Monoarticular
 • Gout (Podagra, Tophi)
 • Pseudogout
 • Early
• Reactive (e.g ... Enteropathic (e.g ... Arthritis • Systemic Lupus ... Sicca) Syndrome ... Enteropathic (e.g
Causes of Fever of Unknown Origin (FUO) - Differential Diagnosis
 • Infection: Extrapulmonary tuberculosis, Abscess, Endocarditis,
Infected thrombosis, (e.g ... Lemierre's syndrome ... Malignancy: - Hematologic ... (e.g. autoimmune ... ): Lupus, Rheumatoid
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... Demyelinating Syndrome ... Cerebrovascular Disease ... Lumbar Puncture, EEG ... CNS #neurology #rheumatology
Neuromyelitis Optica (NMO) - Clinical Manifestations
 • Optic neuritis: Reduced visual acuity, ranging from mild to
Optica (NMO) - Clinical ... (e.g. oculomotor ... (AQP4-lgG disease ... ; e.g. narcolepsy ... disorders (Systemic lupus
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... • Malignancy (e.g ... . hematologic) ... Endocrine disorders (e.g ... Clinical Features
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
• Systemic lupus ... (eg, systemic juvenile ... SJIA], systemic lupus ... • Infection (eg ... Diagnosis #Management #Hematology
Raynaud's Syndrome - Washing off under hot water.
Raynaud phenomenon is an exaggerated vasoconstrictive response of the
Raynaud's Syndrome ... and arterioles (e.g ... #disease #phenomenon ... #clinical #video ... fingers #hands #rheumatology