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diagnosis rheumatology differential hepatology hepatorenal hrs lupus management sle systemic acidosis bruising cerebritis cns cryoglobulinemia cryoglobulins elevation gammopathy hemeonc hemophagocytic
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Cryoglobulins Cause ... tissue disorder (e.g ... systemic lupus erythematosus ... #classification
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Skin Disease Classification ... • Malignancy (e.g ... Endocrine disorders (e.g ... Kikuchi disease • Type-I ... vein thrombosis Hematologic
Hepatorenal Syndrome (HRS) - Diagnostic Criteria HRS-AKI (Acute: previously known as HRS Type 1) • ↑ Creatinine
Hepatorenal Syndrome ... previously known as HRS Type ... nephrotoxics (e.g ... - No other cause ... - No other cause
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Systemic Lupus Erythematosus ... Demyelinating Syndrome ... autoantibodies that will cause ... Lumbar Puncture, EEG ... CNS #neurology #rheumatology
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
by excretion (e.g ... its metabolism (e.g ... - Compartment syndrome ... #typea #typeb # ... classification
Causes of Purpura or Easy Bruising in Children Platelet count reduced, i.e. thrombocytopenia - Increased platelet destruction
systemic lupus erythematosus ... infiltration (e.g ... Rare disorders, e.g ... - Vasculitis, e.g ... #peds #pediatrics
Hepatorenal Syndrome (HRS) Definition: • Functional, potentially reversible kidney impairment. • Occurs in advanced liver disease: cirrhosis, severe alcoholic
Hepatorenal Syndrome ... Exclude other AKI causes ... Classification: ... HRS-AKI (formerly Type ... liver insult (e.g
Monoclonal Gammopathy of Renal Significance (MGRS) MGRS • MGRS refers to kidney disease caused by nephrotoxic monoclonal immunoglobulins
guide subtype classification ... : organized (e.g ... non-organized (e.g ... or no deposits (e.g ... vasculitis Types
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
Types of HLH • ... ▪ Infections (e.g ... pro-inflammatory cytokines (e.g ... Immunosuppression (e.g ... anti-IFN-γ antibodies (e.g
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