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diagnosis differential microscopy acute causes nephrotic proteinuria ain aki biopsy comparison glomerular glomerulonephritis indications injury interpretation interstitial kidney lupus membranoproliferative
Granular & “Muddy Brown” Casts on Urine Microscopy A. Finely granular cast B. slightly coarser granular cast
Urine Microscopy ... “urine poker quads ... #Casts #Urine # ... Microscopy #Clinical ... #Nephrology #Sediment
Nephritic vs Nephrotic Syndrome Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes. Step
Syndrome Step ... /nephritic syndromes ... hematuria (RBC casts ... dysmorphic RBCs in urine ... #Algorithm #Nephrology
Algorithmic Approach to Acute Interstitial Nephritis When to suspect AIN? (not sensitive) • AKI, AKD, rapidly progressive
Algorithmic Approach ... tubular proteinuria, granular ... casts/RTE; blend ... sediment • Received ... #nephrology #diagnosis
Urinary Casts and Disease Associations Hyaline - May be nonspecific; seen in normal individuals or during severe
and concentrated urine ... Granular - May ... Muddy-brown" heme-granular ... syndrome ("Maltese ... edgarvlermamd - Nephrology
Urine Microscopy - Casts Acellular Casts • Hyaline Casts - Consists of only precipitated Tamm-Horsfell protein without
Urine Microscopy ... suggestive of nephrotic ... sydnrome • Pigment ... ) • Granular Casts ... #nephrology #interpretation
Causes of Proteinuria - Differential Diagnosis Algorithm Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
• Fanconi's syndrome ... sediment - WBC/ ... RBC casts ... sediment ... #Proteinuria #Nephrology
Lupus Nephritis - Diagnostic approach to kidney disease associated with systemic lupus erythematosus (SLE) SLE patient develops
urine sediment ... dysmorphic RBCs, RBC casts ... , WBC casts) especially ... #diagnosis #algorithm ... #sle #nephrology
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis Baseline Investigations: full blood count with differential,
Injury - AKI Workup Algorithm ... microscopy / urinary sediment ... investigations depending on clinical ... • Interstitial nephritis ... Differential #Diagnosis #nephrology
Membranoproliferative Glomerulonephritis (MPGN) AKA: Mesangiocapillary GN • Active Urine Sediment (dysmorphic RBC, RBC casts, +/- proteinuria)
GN • Active Urine ... Sediment (dysmorphic ... RBC, RBC casts, ... anti-phospholipid syndrome ... glomerulopathy, radiation nephritis
Algorithm - Approach to the differential diagnosis of the patient presenting with overt glomerular proteinuria. CMV
Algorithm - Approach ... hemolytic-uremic syndrome ... cell/white cell casts ... urine sediment ... #syndrome #nephrology
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