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diagnosis management alkalosis classification disorders metabolic syndrome acutekidneyinjury aki apml basophilia basophils blood differentiation encephalopathy endocrinology eosinophilia essential et gastroenterology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
, CML, AML, APML ... , CLL Acute leukemias ... ALL (Acute Lymphoblastic ... involvement CML ... -> AML: Blast crises
Blood Disorders - Markers and Differential Diagnosis Algorithm Acute • Myloid (AML) - CD13, CD33, CD34,
Acute • Myloid ... (AML) - CD13, CD33 ... • Lymphoid (CLL ... CD23, o CML ... Blood #Disorders #hematology
Hyperuricemia - Differential Diagnosis Algorithm Primary - Over-production • Increased turnover of nucleotides Primary
Diagnosis Algorithm ... Lymphoblastic Leukemia (ALL ... ) • Acute ... Myeloid Leukemia (CML ... endocrinology #causes
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm Volume Depleted - 2° hyperaldosteronism • Low Urine Cl-: Vomiting,
Diagnosis Algorithm ... hyperaldosteronism • Low Urine Cl ... NGT suction, Low Cl ... • High Urine Cl ... #Nephrology #Causes
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Causes of Thrombocytosis ... - Differential ... Thrombocytosis): • Acute ... myeloid leukemia (CML ... #hematology #secondary
Basophilia - Differential Diagnosis Framework Basophils < 1% of the total white blood cell count Basophils function similarly
Basophilia - Differential ... myeloid leukemia (CML ... translocation • Acute ... #Diagnosis #causes ... #hematology #basophils
Causes of Eosinophilia - Differential Diagnosis Bugs: - Fungus (aspergillosis) - Viral (HIV) - Ectoparasites (scabies, myiasis)
Causes of Eosinophilia ... - Differential ... Primary: - CML ... Mastocytosis - Acute ... #hematology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Triggers: ATRA treatment ... • Induce blast cell ... initiation • Differential ... diagnosis #management #hematology ... #oncology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Diagnosis Algorithm ... Treated Like Acute ... relapse - Amy ... pathophysiology #Hematology ... #algorithm
Guide to Acute Kidney Injury (AKI) What to ask/look for: - HPI, PMH, full ROS
Guide to Acute Kidney ... - Urine Na/K/Cl ... AcuteKidneyInjury #AKI #Nephrology ... #Diagnosis #Algorithm ... #Causes #Differential
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