11 results
Hematuria Workup and Diagnosis Algorithm
 • Confirm hematuria → Urinalysis >3 RBCs/HPF, exclude mimics, repeat testing
• Evidence of glomerular ... bleeding (proteinuria ... → Refer to Nephrology ... for renal biopsy ... cystoscopy • Refer to Nephrology
Causes of Proteinuria - Differential Diagnosis Algorithm
Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
Causes of Proteinuria ... • Drugs Glomerular ... albuminuria) - Active ... #Nephrology #Differential ... Diagnosis #Algorithm #Causes
Hematuria - Differential Diagnosis Framework

Gross Hematuria: Red/Dark urine
 • 1ml blood/liter urine can induce color change
or dipstick) Glomerular ... of Glomerular Bleeding ... Brown urine - Proteinuria ... Suggestive of glomerular ... #urology #nephrology
Causes of Chronic Kidney Disease - Differential Diagnosis Algorithm
Decreased kidney function (eGFR < 60 ml/min/1.73 m2)
Causes of Chronic ... Atherosclerosis Glomerular ... (Proteinuria) ... KidneyDisease #Nephrology ... Diagnosis #Algorithm #Causes
Recommended initial testing for patients being evaluated for glomerular disease 

24-hour urine collection - Quantify proteinuria.
evaluated for glomerular ... disorders that activate ... infections are common causes ... #testing #workup ... nephrotic #nephritic #nephrology
Membranoproliferative Glomerulonephritis (MPGN) AKA: Mesangiocapillary GN
 • Active Urine Sediment (dysmorphic RBC, RBC casts, +/- proteinuria)
Mesangiocapillary GN • Active ... , +/- proteinuria ... formation along glomerular ... Glomerulonephritis #MPGN #nephrology ... #diagnosis #renal
Management of Lupus Nephritis
Lupus nephritis (LN) in 10 to 40% of SLE
Hallmark = proteinuria 20.5 g/g
SLE Hallmark = proteinuria ... or 0.5 g/day → renal ... therapy Goal: proteinuria ... Focal LN (<50% of glomeruli ... #rheumatology #nephrology
Recommended initial testing for patients being evaluated for glomerular disease
1) 24-hour urine collection - Quantify proteinuria.
evaluated for glomerular ... disorders that activate ... infections are common causes ... #workup #diagnosis ... initial #testing #nephrology
Renal Biopsy - Absolute and Relative Contraindications
WHEN NOT TO DO IT:
 • Isolated glomerular hematuria, unless
Renal Biopsy - Absolute ... : • Isolated glomerular ... • Low grade proteinuria ... bilateral cysts • Active ... Contraindications #management #nephrology
Causes of Metabolic Alkalosis: Differential Diagnosis
ECF volume contracted: urine chloride concentration <20 meq/L
 • Gastric alkalosis:
Causes of Metabolic ... diuretics after renal ... ectopic ACTH) • Exogenous ... dehydrogenase activity ... #nephrology