959 results
diagnosis symptoms signs management differential cardiology pharmacology endocrinology nephrology syndrome causes algorithm clinical psychiatry ophthalmology neurology msk infectiousdiseases pulmonary complications
Mechanism of Action of Bile Acid Sequestrants Bile Acid Sequestrants → ↓ Hepatic Bile Acid Pool →
HMG-CoA Reductase Expression ... sequestration #pathophysiology
Giant Cell (Temporal) Arteritis: Pathogenesis and investigations Risk Factors: - Unclear environmental triggers (may be viral, not
inflammatory cytokine expression ... Temporal #Arteritis #Pathophysiology
Glucocorticoid-Induced Osteoporosis: Pathogenesis and Clinical Findings • Negative feedback on hypothalamus/pituitary, Decreasing ACTH -> Decr Sex
Upregulate gene expression ... #Osteoporosis #pathophysiology
Feedback Loop: Growth Hormone (GH) Growth Hormone: • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
pathway -> Incr gene expression ... endocrinology #pathophysiology
Xeropthalmia: Pathogenesis and Ocular Manifestations Decr Visual pigment -> Keratinization, thickening & non-wetting of the conjunctiva
& Decr surface expression ... #Xeropthalmia #pathophysiology
Pediatric Parasomnias and Nightmares: Pathogenesis and clinical findings Parasomnias - Micro-arousal episodes during SWS -> Intense activation of
Fearful facial expression ... Pediatrics #Peds #pathophysiology
Aphasia - Pathophysiology and Clinical Findings Broca's Aphasia - Expressive language impairment: non-Fluent - Sensory speech areas
Aphasia - Pathophysiology ... Broca's Aphasia - Expressive ... deficits #Aphasia #Pathophysiology
ACEi/ARBs in COVID-19: Beneficial, Bad, or Benign? Preclinical studies suggest ACEi/ARB use increases ACE2 expression, raising concern
increases ACE2 expression ... #Coronavirus #Pathophysiology
Schizophrenia: Pathogenesis and Symptoms Increased dopaminergic transmission in mesolimbic projection -> Dopaminergic neurons here project into the limbic
Diminished emotional expression ... Schizophrenia #pathophysiology
Major Physiological Effects of Angiotensin II Altered Peripheral Resistance I. Direct vasoconstriction II. Enhancement of peripheral noradrenergic neurotransmission: A.
Increased expression ... AngiotensinII #Pathophysiology
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