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Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Consumption of Clotting Factors ... history of trauma, sepsis ... protein C and S Pathophysiology ... Treat primary cause ... #diagnosis #causes
Summary of Coagulation Deficiencies Inherited: • Hemophilia A - Deficiency of Factor VIII • Hemophilia B -
Summary of Coagulation ... Deficiency of Factor ... • Acute DIC - Septic ... EricsMedicalLectures/ #Coagulation ... Deficiencies #Summary #table
Risk Factors for Septic Arthritis Contiguous spread Skin infection, cutaneous ulcers Direct inoculation Previous intraarticular injection Prosthetic joint: early and delayed
Risk Factors for ... early and delayed (Table ... Osteoarthritis Other cause ... joint: late (Table ... Infective #Arthritis #RiskFactors
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 Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
Acquired Risk Factors ... cardiac valves (septic ... intravascular coagulation ... and other causes ... Venous #Arterial #pathophysiology
Intraoperative Sepsis - Guidelines for Crises in Anaesthesia Severe sepsis (hypotension persisting after initial fluid challenge of
Guidelines for Crises ... likely underlying cause ... lactate, FBC, U&Es, coagulation ... devices could have caused ... central and arterial access
SEPSIS AND SEPTIC SHOCK DEFINITION AND PATHOPHYSIOLOGY • Sepsis: Life-threatening organ dysfunction due to a dysregulated host
DEFINITION AND PATHOPHYSIOLOGY ... • Pathophysiology ... COMMON CAUSES + ... RISK FACTORS • ... • Risk factors
Lung Abscess - Diagnosis and Management Summary Lung Abscess Etiology: • Necrosis of lung parenchyma by a
• Most common cause ... pneumonia • DM risk factor ... Pathophysiology ... shows a small, stable ... #differential #causes
Review of the Coagulation Cascade Traditional Model: • Parallel extrinsic and intrinsic pathways. Contemporary Model: • 4 key
Review of the Coagulation ... Initiation phase caused ... , resulting in coagulation ... EricsMedicalLectures/ #Coagulation ... models #hematology #pathophysiology
Causes of B12 deficiency. This great diagram shows normal absorption and outlines most possible causes. At
Causes of B12 deficiency ... most possible causes ... food protein by peptic ... bind to intrinsic factor ... #Diagnosis #Pathophysiology
Mastoiditis: Pathogenesis and clinical findings Acute or Chronic Otitis Media -> Stage 1: Hyperemeia of the mastoid
destroying thin bony septae ... Subperiosteal abscess ... tip -> Bezold abscess ... hearing loss, nausea ... #Mastoiditis #pathophysiology
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