28 results
Diuretic Electrolyte Excretion Effects 
Diuresis, Na+, K+, Mg2+, Ca2+, Cl-, HCO3-, Uric Acid
 - Thiazide Type
Diuretic Electrolyte Excretion ... Carbonic Anhydrase Inhibitor ... electrolytes #effects #pharmacology ... #comparison #table
DPP-4 Inhibitors - Pharmacology Summary
Mechanisms of Action: Inhibits DPP-4 (dipeptidyl peptidase 4), which normally inactivates GLP-1
DPP-4 Inhibitors ... - Pharmacology ... not definitively cause ... #Pharmacology # ... DM2 #diabetes #endocrinology
Drugs that Impair Renal Potassium Excretion 

Decreased ENaC channel function: Amiloride, Triamterene, Pentamidine
Decreased Aldosterone Synthesis: Heparin,
Renal Potassium Excretion ... Aldosterone Release: ACE inhibitors ... #Hyperkalemia #Pathophysiology ... #Pharmacology #
Hyperuricemia - Differential Diagnosis Algorithm
Primary - Over-production
     • Increased turnover of nucleotides
Primary
Primary - Under-excretion ... Secondary - Under-excretion ... drugs • ACE inhibitors ... Diagnosis #Algorithm #endocrinology ... #causes
SGLT2 Inhibitors 
SGLT2 inhibitors are the newest class of anti-diabetic medications, with the first one (Canagliflozin)
SGLT2 Inhibitors ... kidney), which causes ... increased glucose excretion ... #Pharmacology # ... DM2 #Diabetes #Endocrinology
Tranexamic Acid - Indications and Pharmacology
Pharmacokinetics:
 • MOA: Inhibits plasminogen activation to plasmin & inhibits fibrinolysis
Indications and Pharmacology ... Pharmacokinetics: • MOA: Inhibits ... activation to plasmin & inhibits ... hours • Method of Excretion ... #Indications #Pharmacology
Serotonin-Norepinephrine Reuptake Inhibitors(SNRIs): Mechanisms and Side Effects

Withdrawal: Dizziness, Diarrhea, Insomnia, Nausea, Vomiting
Serotonin Syndrome - Potentially Life
Serotonin-Norepinephrine Reuptake Inhibitors ... gain Incr NE: Nausea ... SerotoninNorepinephrine #Inhibitors ... #Pathophysiology ... #Pharmacology #
Selective Serotonin Reuptake Inhibitors: Mechanisms and Side Effects
 • Serotonin Syndrome:
   - Autonomic Hyperactivity:
Serotonin Reuptake Inhibitors ... Dizziness - Nausea ... SSRIs #Serotonin #Inhibitors ... #Pathophysiology ... #Pharmacology #
Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
share the same pathophysiology ... • Other rare causes ... Excess Insulin Secretion ... signs #symptoms #endocrinology ... #pathophysiology
Hyperuricemia: Pathogenesis and Complications

 - Hypercalcemia (due to diseases like Sarcoidosis and Hyperparathyroidism) -> Accumulation of
tubules - ACE-inhibitors ... nephron -> Decr secretion ... nephron -> Under-excretion ... Release of purine bases ... Hyperuricemia #Pathophysiology