23 results
CREST Syndrome: Pathogenesis and Clinical Findings

CALCINOSIS (BB-sized, hard nodules in fingers)
RAYNAUD'S Phenomenon
ESOPHAGEAL DYSMOTILITY
SCLERODACTYLY (thickening and tightening
Pathogenesis and Clinical ... hard nodules in fingers ... tightening of skin ... #Diagnosis #Signs ... #Symptoms
Cold Urticaria
Prevalence - 0.05% in the population
Disease onset - Mostly 2nd to 4th decades of life
Causes
life Causes and clinical ... and duration of symptoms ... within one hour or longer ... #rheumatology # ... comparison #table
Symptoms Distinguishing Groups of Cutaneous Drug Reactions
IgE-mediated reactions:
 • Onset minutes to hours into treatment course
Symptoms Distinguishing ... Raised off of the skin ... lasts > 24h • Fine ... Drug #Reactions #dermatology ... #clinical #comparison
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Viral Infection Clinical ... nose, ears, or fingers ... of anemia include ... anemia • Cold ... #hematology #diagnosis
Major Depressive Disorder (MDD): Pathogenesis and Clinical Findings

Symptoms (included in DSM 5 criteria) - Present during
Pathogenesis and Clinical ... /pleasure) - Anergia ... ) - Worse in winter ... MoodDisorders #Diagnosis ... #Pathophysiology
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Clinical Features ... Sjögrens (15%) Skin ... ) Blood (75%): Anemia ... erythematosus #signs #symptoms ... #diagnosis #rheumatology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Clinical Presentation ... Headaches • Pale skin ... • Improve the symptoms ... #oncology #hematology ... #diagnosis #management
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
Risk factors: Critical ... blood donor • Pathophysiology ... ARDS to explain symptoms ... Transfusion #Reactions #hematology ... #diagnosis #comparison
Scurvy (Vitamin C Deficiency) - Diagnosis and Management

Vitamin C is required for hydroxylation of proline residues
Deficiency) - Diagnosis ... integrity of: • Skin ... poor nutrition Clinical ... Psychiatric symptoms ... Loss of teeth Anemia
Dermatomyositis (DM) and Polymyositis (PM): Pathogenesis and clinical findings
Elevated Antinuclear Antibodies: Anti-Jo-1, Anti-OJ, Anti-Mi2, Anti-SRP, Anti-EJ,
Pathogenesis and clinical ... processes occur in the skin ... Polymyositis #PM #Diagnosis ... #Pathophysiology ... #Signs #Symptoms