26 results
Symptoms Distinguishing Groups of Cutaneous Drug Reactions
IgE-mediated reactions:
 • Onset minutes to hours into treatment course
Distinguishing Groups of Cutaneous ... lasts > 24h • Fine ... or severe cutaneous ... #dermatology #clinical ... #comparison #classification
Approach to the Rash in a an oncology patient - MINT-C Mnemonic
M - Malignancy: Leukemia cutis,
Approach to the Rash ... Leukemia cutis, Cutaneous ... Adverse Reactions ... #differential #diagnosis ... MINTC #Mnemonic #dermatology
Warm vs Cold Autoimmune Hemolytic Anemia
Warm Autoimmune Hemolytic Anemia:
 • Mechanism: IgG and Complement-mediated
 • Etiology:
Warm vs Cold Autoimmune ... Immunosuppression, Splenectomy Cold ... BostonChiefs #Warm #Cold ... Hemolytic #Anemia #hematology ... #diagnosis #comparison
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... Other: Transfusion reaction ... Autoimmune (AIHA)"Cold ... (e.g. primary cold ... #hematology #anemia
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
- Differential Diagnosis ... Autoimmune: Warm AIHA, Cold ... AIHA, Transfusion reactions ... #Differential #Diagnosis ... #hematology
Differential Diagnosis for Hemolytic Anemia
Intrinsic Causes:
 • Enzyme deficiencies ex. G6PD, pyruvate kinase 
 • Hemoglobinopathies
Differential Diagnosis ... • AIHA: warm, cold ... • Transfusion reactions ... #Differential #Diagnosis ... classification #hematology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
nose, ears, or fingers ... presentation) • Cutaneous ... Diagnosis: • hemolytic ... hemolytic #anemia #hematology ... #diagnosis
Orf Virus - Cutaneous Finger Lesions

35 year old butcher presents with these lesions one week after
Orf Virus - Cutaneous ... Finger Lesions ... 35 year old butcher ... #Finger #clinical ... #photo #dermatology
Cold Urticaria
Prevalence - 0.05% in the population
Disease onset - Mostly 2nd to 4th decades of life
Causes
within one hour or longer ... Disorientation, vertigo Diagnostic ... #Urticaria #diagnosis ... #rheumatology # ... comparison #table
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
- Transfusion Reactions ... #Transfusion #Reactions ... #hematology #diagnosis ... #comparison #table