36 results
ANA Patterns and Associated Rheumatic Diseases:
 • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
erythematosus (SLE ... ), Sjogren's Syndrome ... #Antinuclear #Antibodies ... ANA #patterns #rheumatology ... #diagnosis #differential
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
Autoimmune • ITP • SLE ... Alloimmune • anti-HLA antibodies ... Non-lmmune: • HELLP Syndrome ... HUS • DIC • Vasculitis ... Algorithm #Causes #Hematology
Autoantibodies in Rheumatology
 • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Autoantibodies in Rheumatology ... • Lupus (SLE): ... others (RNP, aPL antibodies ... • Scleroderma (Systemic ... Autoantibodies #Rheumatology
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
La) - Sjogren's syndrome ... disease c-ANCA - Vasculitis ... granulomatosis p-ANCA - Vasculitis ... diagnosis #table #rheumatology ... #antibodies
Vasculitis Involving the Skin - Differential Diagnosis Framework

Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis
Secondary: CTD: SLE, RA
the Skin - Differential ... Secondary: CTD: SLE ... Disease • Cogan syndrome ... #rheumatology # ... differential #diagnosis
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies)
 • Systemic lupus erythematosus
   1. Anti-dsDNA
) • Systemic lupus ... in drug-induced SLE ... ) • Systemic sclerosis ... cases • Sjögren syndrome ... #diagnosis #rheumatology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
→ Refer to hematology ... for workup, including ... , Vasculitides, ... Kawasaki, Nephrotic syndrome ... Diagnosis #Algorithm #hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... Kasabach-Merritt syndrome ... Associated - SLE ... #Diagnosis #hematology ... #rheumatology #
Aortitis - Differential Diagnosis Framework
Non-Infectious Aortitis:
 • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
Aortitis - Differential ... arteritis, Cogan's Syndrome ... Arthritis (RA), Systemic ... erythematosus (SLE ... #Diagnosis #rheumatology
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Hypersensitivity vasculitis ... Antiphospholipid-antibody syndrome ... • Vasculitis ... #skin #rashes #differential ... #diagnosis #rheumatology