32 results
Thrombocytosis - Differential Diagnosis
Platelet Count > 450
Reactive:
 • Anemia/blood loss (Fe deficiency)
 • Infection/Sepsis
 • Non-infectious
Reactive: • Anemia ... blood loss (Fe deficiency ... ) • Infection/ ... (malignancy, rheumatologic ... Myelofibrosis • Chronic
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Low Mean Corpuscular Volume (<80
Volume (MCV) - Differential ... 80 fL) • Iron Deficiency ... Infection) High ... Classification #Differential ... Algorithm #Causes #Hematology
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased WBCs
 - Decreased/NormaI
Volume (MCV) - Differential ... RA, SLE, PRV, Chronic ... Spherocytes, RBC Fragments ... • Early Iron Deficiency ... #Differential #
Anemia - Underproduction Diagnostic Algorithm
 - Iron deficiency anemia
 - Anemia of chronic inflammation
 - Anemia
Algorithm - Iron deficiency ... of chronic inflammation ... - Anemia of chronic ... and/or folate deficiency ... #diagnosis #differential
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor
The maturation factor is
deficiencies: Iron deficiency ... (e.g. cancer, infection ... , G6PD deficiency ... ), Infections, Hypersplenism ... #anemia #differential
Diagnostic Framework for Anemia (Morphological Approach - MCV)
Low MCV - <80fL - "Microcytic"
 • Iron deficiency
of chronic inflammation ... of chronic kidney ... , Folate deficiency ... morphologic #mcv #differential ... diagnosis #causes #hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Thrombocytosis - Differential ... Myelofibrosis Infectious ... malignancy • Iron deficiency ... anemia #Thrombocytosis ... #Differential #
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV

Microcytic (MCV < 80) "TAILS":
 • Thalassemia
- Differential ... Macroangiopathic, Infections ... , B12 deficiency ... MCV #Algorithm #Differential ... #Diagnosis #hematology
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
anemia, Chronic ... myeloma Rouleaux: Chronic ... Multiple myeloma, Chronic ... RBC #Morphology #differential ... #diagnosis #hematology
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
- Differential ... RBCs on Smear • Chronic ... • B12/Folate Deficiency ... • Anemia of Chronic ... Algorithm #Causes #Hematology