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diagnosis hematology hepatology anemia classification liver anemias approach bilirubin bilirubinemia chemistry direct extravascular gastroenterology hemolysis hepatitis hyperbilirubinemia injury interpretation intravascular
Hemolytic Anemias - Differential Diagnosis Algorithm Signs of anemia and hemolysis: • ↓ Haptoglobin • ↑ LDH
- Differential ... Diagnosis Algorithm ... • ↑ Indirect / unconjugated ... Reticulocytes • Abnormal ... #Diagnosis #Algorithm
Jaundice - Differential Diagnosis Algorithm Pre-Hepatic - Unconjugated Hyperbilirubinemia Increased Production • Hemolysis • Ineffective Erythropoiesis • Hematoma Decreased
Jaundice - Differential ... Diagnosis Algorithm ... Production • Hemolysis ... II) Hepatic - Conjugated ... #Causes #Hepatology
Approach to Conjugated Hyperbilirubinemia - Differential Diagnosis Algorithm 1. Definition: T.bili elevation + >20% conjugated 2. Obtain RUQ
Hyperbilirubinemia - Differential ... Diagnosis Algorithm ... Definition: T.bili elevation ... non-ICU vs ICU causes ... #Diagnosis #Algorithm
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Causes of Anemia ... Volume (MCV) - Differential ... Diagnosis Algorithm ... Bleed • Hemolysis ... #Causes #Hematology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Causes of Extravascular ... - Differential ... Diagnosis Algorithm ... Drug-induced AIHA - Abnormal ... #Causes #Hematology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Liver Injury - Differential ... Diagnosis Algorithm ... Vascular Causes ... Bilirubin - +/- elevation ... #diagnosis #algorithm
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
levels - Usually normal ... decrease in most cases ... Mild-to-moderate elevation ... WBC count and differential ... hematuria (without casts
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Bilirubin - +/- elevation ... or amyloid: • Elevation ... of Liver Enzyme Elevation ... blood cells Unconjugated ... chemistry #diagnosis #differential
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Causes of Anemia ... Volume (MCV) - Differential ... Diagnosis Algorithm ... Chronic Disease Normal ... • Bleeding • Hemolysis
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
Approach to Anemia - Differential ... Diagnosis Algorithm ... RBC Production - Normal ... #Diagnosis #Algorithm ... #Causes #Hematology
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