51 results
Nephron Pathophysiology - Diuretic Sites of Action
Diuretics
1) Acetazolamide/canagliflozin
2) Osmotic agents (mannitol, urearetics)
3) Loop agents (eg, furosemide)
4)
Nephron Pathophysiology ... urearetics) 3) Loop ... agents (eg, furosemide ... Adenosine #Nephron #Pathophysiology ... Sites #Action #nephrology
Hormones Acting on the Nephron - Diuretics and Their Site of Action
 1) Acetazolamide
 2) Osmotic
mannitol) 3) Loop ... Diuretics (e.g. furosemide ... spironolactone) #Pathophysiology ... #Nephrology #Nephron
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 • Normal Acid-Base: Low intake
 • Metabolic acidosis: Gl tract
Differential Diagnosis Algorithm ... Normal Acid-Base: Low ... • HTN Absent: Loop ... Differential #Diagnosis #Algorithm ... #low #nephrology
Causes of Metabolic Alkalosis - Differential Diagnosis Algorithm
GI Losses - Gastric
 • Vomiting
 • NG suction
GI
Differential Diagnosis Algorithm ... • Diuretics (loop ... aldosteronism Low ... MetabolicAlkalosis #NonGap #Nephrology ... Differential #Diagnosis #Algorithm
Pathophysiology Based Approach to Hyponatremia - Diagnostic Algorithm

Not the "classic" Volume based approach. 

#Hyponatremia #Algorithm #Pathophysiology
Pathophysiology ... Not the "classic ... #Hyponatremia #Algorithm ... #Pathophysiology ... #Differential #Nephrology
Diuretics - Pharmacology

Thiazides diuretics:
 • Inhibit Na+ Cl- cotransporter in distal tubule
 • Chlorothiazide, Chlorthalidone, Indapamide,
Metolazone Loop ... • Bumetanide, Furosemide ... #Pharmacology #nephrology ... #conversion #loop ... #thiazide #classes
Drugs associated with hypokalemia and hypomagnesemia

Hypokalemia
- Shift from extracellular fluid to intracellular fluid compartment
  -
Acetazolamide - Furosemide ... and other loop ... Diuretics - Furosemide ... differential #diagnosis #nephrology ... #Causes #hypomg
Hyponatremia - Differential Diagnosis Algorithm
ADH Independent:
 • Tea and Toast Syndrome, Beer Potomania - Low solute
Differential Diagnosis Algorithm ... Beer Potomania - Low ... or other losses ... Differential #Diagnosis #Algorithm ... #causes #nephrology
NSAIDS and their effects on the Kidney - Pathophysiology

Arachidonic Acid metabolites into alternative pathways that modify
on the Kidney - Pathophysiology ... reabsorption in Proximal, loop ... decreased renal blood flow ... KidneyDisease #nephrology ... #Effects #pathophysiology
Hypokalemia - Differential Diagnosis Algorithm

Transcellular Shift:
 • Alkalosis
 • ↑ beta-2 adrenergic simulation 
 • Erythropoiesis
Differential Diagnosis Algorithm ... : • GI losses ... vomiting) • Low ... Differential #Diagnosis #Algorithm ... #nephrology #low