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management differential hematology oncology signs sle systemic erythematosus nephrology syndrome algorithm causes classification summary syndromes arthritis infectiousdiseases monoclonal sclerosis vasculitis
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
(SLE) - Diagnosis ... • Immunologic Workup ... life-threatening • Treatment ... Evolution: Chronic disease ... Management #Summary #rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Cerebrovascular Disease ... permeability Diagnosis ... Erythematosus #SLE #CNS #neurology ... #rheumatology # ... cerebritis #diagnosis
BEE Syndromes - Immune-mediated conditions affecting the brain, eye, and ear Visual or auditory symptoms in conjunction
Visual or auditory symptoms ... conjunction with symptoms ... and treatment can ... syndrome • Systemic lupus ... BEE #Syndromes #neurology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms ... • Treatment: ... Evolution: Chronic disease ... comparison #table #rheumatology ... #diagnosis #management
Common causes of Acute Kidney Injury AKI - Differential Diagnosis HEMODYNAMIC • Cardiac failure: Impaired forward flow,
- Differential Diagnosis ... • Primary GNs: Disease ... Post-infectious GN ... , Lupus Acute Tubular ... #nephrology
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
Complement: Post-strep GN ... , Lupus Nephritis ... involvement: Anti-GBM Disease ... #differential #diagnosis ... #algorithm #rheumatology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
- Diagnosis Manifestations ... auto-immune, Infectious diseases ... sclerosis, Still's disease ... autoantibodies #signs #symptoms ... #differential #rheumatology
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
context of other symptoms ... , Drug-induced Lupus ... , Drug-Induced Lupus ... ANA #patterns #rheumatology ... #diagnosis #differential
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Systemic Lupus Erythematosus ... Treatment: • ... #Systemic #Lupus ... #SLE #Summary #diagnosis ... #rheumatology #
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis Neurologic-Centered: (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
- Differential Diagnosis ... Neurologic-Centered ... Ig deposition disease ... #Differential #Diagnosis ... #hematology #oncology
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