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diagnosis differential thrombocytopenia aflp comparison hellp obstetrics ttphus algorithm apls arterial associations autoantibodies champs classification complement embolism framework hypercoagulable hypocomplementemia
Autoantibodies in Rheumatology • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Autoantibodies in Rheumatology ... • Lupus (SLE): ... antibodies) • Antiphospholipid ... Autoantibodies #Rheumatology ... #associations #table
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP) Three syndromes in
TTP/HUS, HELLP Syndrome ... (AFLP) Three syndromes ... child * Severe cases ... AFLP #obstetrics #hematology ... #diagnosis #table
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Causes of Hypocomplementemia ... RA, Sjogren's), antiphospholipid ... syndrome, atheroembolic ... S - Systemic Lupus ... #differential #hematology
Thrombocytopenia and Pregnancy Three syndromes in the critically ill pregnant woman who presents with coagulation defects. 1) HELLP
Three syndromes ... critically ill pregnant ... child * Severe cases ... Obstetrics #OBGyn #Hematology ... Diagnosis #Comparison #Table
Causes of Thrombocytopenia - Differential Diagnosis Framework Decreased Production: - Drugs (chemo, yang, sulfa, acetaminophen, NSAIDs, quinine,
Causes of Thrombocytopenia ... Autoimmune: SLE, RA, antiphospholipid ... syndrome - Pregnancy ... Diagnosis #Framework #hematology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
Intravenous Drug Use • Pregnancy ... • Nephrotic Syndrome ... Malignancy - Antiphospholipid ... coagulation and other causes ... pathophysiology #hematology
Antiphospholipid Syndrome (APLS) Testing - Hypercoagulable Workup Algorithm INDICATIONS FOR TESTING: • Vascular thrombosis
Antiphospholipid ... • Unexplained pregnancy ... maternal chromosomal causes ... excluded Testing: • Lupus ... Algorithm #diagnosis #hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
rapidly progressing GN ... tract, and often causes ... inflammation Others: • Lupus ... such as systemic lupus ... differential #diagnosis #rheumatology
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