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diagnosis differential management erythematosus sle symptoms syndrome classification vasculitis disease myositis oncology activation algorithm antibodies antinuclear aortitis arteritis autoantibodies behcet
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
Inflammatory and ... Autoimmune Diseases ... : • Systemic lupus ... • Epstein-Barr virus ... Differential #Diagnosis #Hematology
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
assay (IFA) is the main ... Positive ANA ≠ Autoimmune ... Juvenile Idiopathic Arthritis ... Thyroid, Autoimmune ... #patterns #rheumatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Lupus (SLE) General ... of hip (rare), Arthritis ... lesions Abdominal pain ... erythematosus #signs ... symptoms #diagnosis #rheumatology
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
Classification Criteria for Systemic ... • Arthritis domain ... Thrombocytopenia, Autoimmune ... low C4, Low C3 and ... #diagnosis #rheumatology
Causes of Isolated Neutropenia - Differential Diagnosis Algorithm Congenital Medications • Anticonvulsants • Antibiotics • Antithyroid • Antihypertensive
• Epstein-Barr Virus ... Destruction • Systemic ... Lupus Erythematosus ... • Rheumatoid Arthritis ... Algorithm #Causes #Hematology
Autoimmune Myositis Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
Autoimmune Myositis ... weakness, less systemic ... , holster sign, ... arthritis (19% ... Myositis #diagnosis #rheumatology
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Atypical HUS, autoimmune ... glomerulonephritis (>90%) S - Systemic ... Lupus Erythematosus ... Ann Marie Kumfer ... #differential #hematology
Aortitis - Differential Diagnosis Framework Non-Infectious Aortitis: • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
Polyarteritis Nodosa (PAN ... ), ANCA associated ... (RA), Systemic ... lupus erythematosus ... Differential #Diagnosis #rheumatology
Combination of Skin Findings and Arthritis in Pediatrics Patient - Differential Diagnosis Malar rash: • A
Skin Findings and ... Suggestive of: Lupus ... migrans: • Target sign ... Suggestive of systemic ... gabrieltalledop #dermatology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Systemic Lupus Erythematosus ... Manifestations: - Arthritis ... Auto-Antibodies: - ANA ... autoantibodies #signs ... #differential #rheumatology
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