401 results
diagnosis differential management rheumatology algorithm causes pharmacology treatment table clinical sle medications nephrology erythematosus dermatology hematology neurology pathophysiology systemic signs
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
Post-strep GN, Lupus ... Henoch-SchonIein Purpura Anti-GBM ... Limited to Kidney: Anti-GBM ... pulmonary involvement: Anti-GBM ... Disease (Goodpasture's
Pulmonary Renal Syndrome Definition: Diffuse alveolar hemorrhage + Glomerulonephritis Presentation (Pulmonary and renal manifestations can occur weeks apart):
Complex: Systemic lupus ... sclerosis • Anti-Glomerular ... Basement Membrane: Goodpasture's ... ab, anti-GBM ab ... , ANA, C3, C4, anti-CCP
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Systemic Lupus Erythematosus ... 5-10% - Anti- ... Diagnosis and Lupus ... : Drug-induced lupus ... SLE #Systemic #Lupus
Antinuclear antibodies and Systemic lupus Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can
antibodies and Systemic lupus ... Farr assay) and lupus ... & drug-induced lupus ... SCLE, neonatal lupus ... Sjogren and neonatal lupus
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
- SLE Anti-histone ... (AMA), Anti-sp100 ... - SLE Anti-SSA ... (Ro), Anti-SSB ( ... - Goodpasture's
I’M DAMN SHARP - Lupus Diagnosis Mnemonic I Immunoglobulins (Anti-dsDNA, Anti-Sm, Anti-phospholipid) M Malar Rash D
M DAMN SHARP - Lupus ... Immunoglobulins (Anti-dsDNA ... , Anti-Sm, Anti-phospholipid ... sle #systemic #lupus
Autoantibodies in Rheumatology • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Rheumatology • Lupus ... , Anti-Ro (SSA) ... and Anti-La (SSB ... glycoprotein I (ß2GP), Lupus ... (SSA), Anti-La
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Drug Induced Lupus ... Drug Induced Lupus ... Epidemiology: -10% of all lupus ... years) Systemic Lupus ... , oral ulcers, Lupus
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
Criteria for Systemic Lupus ... Acute cutaneous lupus ... IgG > 40 GPL or anti-ß2GPI ... antibodies domain: Anti-dsDNA ... antibody, Anti-Sm
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... , oral ulcers, Lupus ... ANA > - Anti-ENA ... to 30% - Anti-dsDNA ... Lupusreference #SLE #lupus
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