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diagnosis management rheumatology hemophagocytic hlh lymphohistiocytosis candida candidemia cellulitis cerebritis cns coagulation dic differential disease disseminated erythematosus fungemia gammopathy hemeonc
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
organ damage Clinical ... + Bleeding Treatment ... Treat primary cause ... #treatment #management ... #hematology
Clinical Classification of Pulmonary Hypertension 1. Pulmonary arterial hypertension from pulmonary vasculopathy Idiopathic pulmonary arterial hypertension Heritable gene mutations
Clinical Classification ... disease Systolic dysfunction ... Diastolic dysfunction ... multifactorial mechanisms Hematologic ... #Differential #Causes
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Assessment • Clinical ... , Hb), Hepatic dysfunction ... Drugs, Unknown cause ... Treatment: •
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... Encephalopathy, Cognitive Dysfunction ... autoantibodies that will cause ... Puncture, EEG Treatment ... CNS #neurology #rheumatology
Hepatorenal Syndrome (HRS) Definition: • Functional, potentially reversible kidney impairment. • Occurs in advanced liver disease: cirrhosis, severe alcoholic
Diagnosis (Clinical ... Exclude other AKI causes ... Classification: ... Treatment Overview ... Hepatorenal #Syndrome #Hepatology
IDSA Algorithm for the Management of Purulent skin and soft tissue infections (SSTIs). Mild infection: for
IDSA Algorithm for ... oral antibiotic treatment ... or those with clinical ... evidence of organ dysfunction ... including those caused
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Hodgkin Lymphoma - Clinical ... ) Classification ... Hodgkin Lymphoma Treatment ... lymphoma #diagnosis #classification ... #hematology #oncology
Von Willebrand Disease Classification Type 1 (Accounts for ~3/4 of cases): • Defect: Quantitative defect (i.e. not
Willebrand Disease Classification ... Qualitative defect (i.e. dysfunctional ... Bleeding: Severe (Clinically ... VonWillebrand #Disease #Classification ... Types #diagnosis #hematology
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
cytopenias and organ dysfunction ... hyperinflammatory syndrome caused ... Persistent fever, organ dysfunction ... Clinical Presentation ... Diagnosis #Management #Hematology
Invasive Fungal Infection (IFI) Invasive fungal infections are severe infections in which fungal pathogens invade normally sterile
with neutropenia, hematologic ... (most frequent cause ... antibiotic exposure Clinical ... include fever, organ dysfunction ... virulence Delays in treatment
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