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Risk factors for atherosclerosis Modifiable risk factors: - Dyslipidemia (elevated LDL, decreased HDL) - Tobacco smoking -
Dyslipidemia (elevated LDL ... , decreased HDL)
Abnormal Lipid Profiles - Differential Diagnosis Algorithm Increased Cholesterol and Triglycerides - Genetic Causes
Hypothyroidism Decreased HDL ... Androgens Increased LDL
Fibrates - Gemfibrozil and Fenofibrate Mechanism: activates PPAR alpha Lipid Effects: - Decrease TG by 30-50% -
50% - Increase HDL ... - Decrease LDL
Mechanism of Action of Bile Acid Sequestrants Bile Acid Sequestrants → ↓ Hepatic Bile Acid Pool →
/Secretion → ↑ LDL ... Production → ↑ LDL ... Receptors → ↑ LDL ... Clearance → ↓ Plasma LDL-C
Liver Disease in Pregnancy Intrahepatic Cholestasis of Pregnancy (ICP) • Onset/Trimester: 25-32 weeks • Typical clinical features:
weeks • Typical clinical ... Bilirubin: <5 mg/dL ... post-partum • Typical clinical ... Bilirubin: <5 mg/dL ... post-partum • Typical clinical
Classification of Tumor Lysis Syndrome (TLS) and Treatment of Metabolic Abnormalities of TLS Laboratory TLS: • Uric
acid ≥ 8.0 mg/dL ... Potassium ≥ 6.0 mEq/dL ... Phosphorus ≥ 4.6 mg/dL ... Calcium ≤ 7.0 mg/dL ... Clinical TLS:
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Hodgkin's lymphoma (HL ... Hodgkin Lymphoma - Clinical ... • Classical HL ... rich classical HL ... diagnostic for HL
Multiple Myeloma and Monoclonal Gammopathies C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN R
calcium > 11 mg/dL ... / >1 mg/dL the ... disease - Cr >2 mg/dL ... Hemoglobin < 10 g/dL ... or <2 g/dl LLN
Algorithm in Suspected Bacterial Peritonitis - Infographic by IDagram @ID_agram Runyon Criteria for Secondary Peritonitis (two of the
total protein >1 g/dL ... glucose <50 mg/dL
Suggested algorithm for bone marrow biopsy and skeletal imaging in patients with monoclonal gammopathy of undetermined
small (<1.5 gm/dL ... protein <1.5 gm/dL ... whom there are no clinical
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