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diagnosis management cardiology differential heartfailure iron mds myelodysplastic syndrome anemia aplastic dermatology emergencies guidelines hemeonc myelodysplasia oncologic sweet syndromes thrombocytopenia
Iron Deficiency in Heart Failure - Diagnosis and Treatment Algorithm Diagnosis: Ferritin <100 ng/mL (absolute ID) OR
Diagnosis and Treatment ... Algorithm Diagnosis ... NYHA class II and Ill ... HF with iron deficiency ... #CHF #HFrEF #heartfailure
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Causes of Thrombocytosis ... Chronic Myelogenous Leukemia ... effect following treatment ... malignancy • Iron deficiency ... #Causes #Hematology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Causes of Thrombocytopenia ... Leukemia, Tumour ... • Folate Deficiency ... ITP • SLE • CLL ... #Causes #Hematology
Iron Deficiency in Heart Failure Pathophysiology: Chronic heart failure leads to an increase in inflammatory cytokines → Inflammation
Iron Deficiency ... → Inflammation causes ... functional ID) Treatment ... composite endpoint of all-cause ... #CHF #HFrEF #heartfailure
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
old, ~10,000 new cases ... transformation to acute leukemia ... Allogeneic stem cell ... only curative treatment ... #hematology #oncology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Leukemia • Idiopathic ... or folic acid deficiency ... • Copper deficiency ... Syndromes #diagnosis #hematology ... #oncology
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
general feeling of ill ... Causes: - Idiopathic ... , breast CA - Hematologic ... Treatment: - Systemic ... #oncology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
and petechiae Causes ... virus (EBV) • Leukemia ... aplastic anemia Treatment ... Aplastic #Anemia #oncology ... #hematology #diagnosis
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
Summary of Oncologic ... syndrome): - Hematologic ... Treat underlying cause ... Usually myeloid leukemias ... ± tocilizumab; call
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