55 results
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Causes of Thrombocytopenia ... - Differential Diagnosis ... family history - Medications ... test, ANA (e.g., SLE ... #hematology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
Causes of Thrombocytopenia ... Autoimmune • ITP • SLE ... Quinidine • HIT ... #Algorithm #Causes ... #Hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
disorders • Celiac disease ... effect following treatment ... following EtOH induced thrombocytopenia ... #Algorithm #Causes ... #Hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... : - Thrombocytopenia ... Associated - SLE ... #hematology #rheumatology ... #nonpalpable #dermatology
Approach to suspected Heparin-Induced Thrombocytopenia (HIT)

 • Suspected HIT Algorithm
 • "4 T's" clinical probability score:
HIT Algorithm ... • "4 T's" clinical ... #HIT #hematology ... #diagnosis #4Ts ... #algorithm
Causes of Thrombocytopenia - Differential Diagnosis Framework
Decreased Production:
 - Drugs (chemo, yang, sulfa, acetaminophen, NSAIDs, quinine,
Causes of Thrombocytopenia ... - Differential Diagnosis ... etc) - Viral: HIV ... - Autoimmune: SLE ... #Framework #hematology
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm
Thrombocytopenia - Quantitative Defect
 • Decreased Production
 •
Causes of Bleeding ... - Differential Diagnosis ... Algorithm Thrombocytopenia ... #Algorithm #Causes ... #Hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
→ Refer to hematology ... Rebound effect from treatment ... Vasculitides, IBD, Celiac disease ... • Reaction to Medications ... #Algorithm #hematology
Von Willebrand Disease - Most common inherited bleeding disorder 
Clinical 
 • Easy bruising 
 •
Von Willebrand Disease ... bleeding disorder Clinical ... platelet count (mild thrombocytopenia ... factor VIII) Treatment ... #Diagnosis #Hematology
Our approach to the diagnosis and initial management of patients with suspected HIT. Our approach is
based primarily on clinical ... and to adjust treatment ... #Hematology #HIT ... Heparin #Induced #Thrombocytopenia ... #Algorithm