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management differential syndrome reactions treatment product rheumatology transfusion alkaline alp associated cauda caudaequina cerebritis coagulation comparison dementia dic disorder disseminated
Guillain-Barre Syndrome - Summary Acute AIDP that presents with rapidly progressive flaccid weakness Epidemiology: • 1-2 cases/100,000 per
Guillain-Barre Syndrome ... AIDP that presents ... than females Guillain-Barre ... bulbar muscles Guillain-Barre ... • Areflexia Guillain-Barre
Etiologies of Peripheral Neuropathy • Metabolic / Nutritional: DiabetesB12 deficiency, Uremia/ESRD, Hypothyroidism • Medication-induced: ART, Antibiotics,
• Infectious: HIV ... Inflammatory/AI: CIDP, Guillain-Barre ... Fabry's disease, Acute ... #differential #diagnosis ... #causes #neurology
Guillain-Barré Syndrome (GBS) Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness Epidemiology: • Incidence: 1
Guillain-Barré Syndrome ... (GBS) Acute autoimmune ... normal CSF white blood ... the underlying pathophysiology ... #neurology
Causes of Secondary Hypertension - Workup and Differential Diagnosis Approach (when evaluation should be done): 1. Severe or
and Differential Diagnosis ... heart failure, neurologic ... Neurologic disorders ... dysautonomia, and Guillain-Barre ... #Differential #Diagnosis
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... Disease, PRES Pathophysiology ... autoantibodies that will cause ... thrombosis and/or blood-brain ... #neurology #rheumatology
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
of high parity blood ... without other cause ... At least 3 of (Acute ... Transfusion #Reactions #hematology ... #diagnosis #comparison
HIV-Associated Neurocognitive Disorder (HAND) Definition: HIV-Associated Neurocognitive disorders categories: • Asymptomatic neurocognitive impairment • Mild neurocognitive impairment • HIV dementia Pathophysiology: HIV frequently
dementia Pathophysiology ... and infects the CNS ... Diagnosis: MRI ... disorder #dementia #AIDS ... #Neurology
Cauda Equina Syndrome Overview Cauda Equina Syndrome: • Prevalence: 1:33,000-100,000 ppl/yr • Incidence: 1.5-3.4 million ppl/yr •
spine • MCC- acute ... equina syndrome (CES ... - Emergency Causes ... Tethered cord • Guillain-Barre ... #causes #neurology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
involvement • 30%: CNS ... -> AML: Blast crises ... leukostasis syndrome: CNS ... #Leukemia #Hematology ... #Oncology #Diagnosis
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
malignancy (Especially acute ... ABO incompatible blood ... Thromboembolism (7%) • CNS ... #Coagulation #diagnosis ... #management #hematology
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