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differential antinuclear management sle signs table vasculitis classification patterns treatment antibody antineutrophil arthritis associations cerebritis cns comparison cryoglobulinemia cryoglobulins druginduced
BEE Syndromes - Immune-mediated conditions affecting the brain, eye, and ear Visual or auditory symptoms in conjunction
BEE Syndromes - ... less common diseases ... • Systemic lupus ... spectrum disorder • ANCA-associated ... #Syndromes #neurology
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Positive ANA ≠ Autoimmune ... • +ANA can be seen ... SLE), Sjogren's Syndrome ... Arthritis, Sjögren Syndrome ... #rheumatology #diagnosis
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
ANA Patterns and ... Associated Rheumatic Diseases ... connective tissue disease ... SLE), Sjogren's Syndrome ... #rheumatology #diagnosis
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
Autoantibodies and ... Anticentromere - CREST syndrome ... La) - Sjogren's syndrome ... c-ANCA - Vasculitis ... Goodpasture's syndrome
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
) • Systemic lupus ... cases • Sjögren syndrome ... connective tissue disease ... #diagnosis #rheumatology ... #diseases
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
rheumatologic diseases ... lymphoma • Evans' syndrome ... Shrinking lung syndrome ... • (-) ANA + (+ ... #Diagnosis #Rheumatology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Systemic Lupus Erythematosus ... : - ANA 95-100% ... auto-immune, Infectious diseases ... sclerosis, Still's disease ... #Diagnosis #autoantibodies
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Lupus Erythematosus ... Demyelinating Syndrome ... Cerebrovascular Disease ... #Lupus #Erythematosus ... #rheumatology #
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings • Primary Sjögren's is a solitary process whereas secondary Sjögren's
Primary Sjogren’s Syndrome ... diseases • In ... Sjögren's, the syndrome ... diseases like rheumatoid ... lupus erythematosus
Antinuclear antibodies and Systemic lupus Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can
and Systemic lupus ... Association with disease ... SLE-SSc-AlM overlap syndromes ... with auto-immune diseases ... #diagnosis #rheumatology
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