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ana antinuclear associations erythematosus patterns table antibody antineutrophil aortitis arthritis autoimmune classification conditions hematology laboratory mimickers monoclonal myopathy oncology pain
Autoantibodies in Rheumatology • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Lupus (SLE): ANA ... others (RNP, aPL antibodies ... Peptide (CCP) • Myositis ... • Scleroderma (Systemic ... Vasculitis: P-ANCA
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
their Disease Associations ... c-ANCA - Vasculitis ... (TTG) - Celiac disease ... #Associations #diseases ... antibodies
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
: Systemic lupus ... (SLE), Systemic ... • Rheumatic Diseases ... : Lupus (SLE), Systemic ... #rheumatology #diagnosis
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
Associated Rheumatic ... Diseases: • Homogeneous ... connective tissue disease ... (SLE), Systemic ... #rheumatology #diagnosis
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
) • Systemic lupus ... connective tissue disease ... 90% • Anti-GBM disease ... #diagnosis #rheumatology ... #diseases
Aortitis - Differential Diagnosis Framework Non-Infectious Aortitis: • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
polychondritis, Behcet's Disease ... Nodosa (PAN), ANCA ... Diseases: IgG4- ... Related Disease ... #Diagnosis #rheumatology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Systemic Lupus Erythematosus ... Diagnosis and Lupus ... auto-immune, Infectious diseases ... sclerosis, Still's disease ... #Systemic #Lupus
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Diagnosis: • ANCA-associated ... vasculitis, rheumatoid ... diseases (i.e. ... #Systemic #Lupus
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
(Granulomatous disease ... Diagnosis: Systemic ... rheumatic diseases ... atherosclerotic disease ... differential #diagnosis
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
, SLE, Rheumatic ... , Lyme disease, ... Vasculitis (e.g. ... #pain #differential ... #diagnosis #rheumatology
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