59 results
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
Causes of Bone/Joint ... XR, MRI to dx and ... dz difficult to see ... • Differentiate ... #hematology
Hydroxychloroquine Serum Measurement in SLE
 • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
Measurement in SLE ... concentration: > 750ng/mL and ... #Measurement #SLE ... #rheumatology # ... pharmacology #levels
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential ... test, ANA (e.g., SLE ... or if a primary hematologic ... Platelet #Disorders #Differential ... #Workup #hematology
Aortitis - Differential Diagnosis Framework
Non-Infectious Aortitis:
 • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
Aortitis - Differential ... Polyarteritis Nodosa (PAN ... erythematosus (SLE ... MD @MithuRheu and ... #Diagnosis #rheumatology
Tranexamic Acid - Indications and Pharmacology
Pharmacokinetics:
 • MOA: Inhibits plasminogen activation to plasmin & inhibits fibrinolysis
- Indications and ... Pharmacology Pharmacokinetics ... diarrhea & abdominal pain ... #Indications #Pharmacology ... #hematology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Erythematosus (SLE ... ) - Diagnosis and ... Positive in 60-80% of cases ... life-threatening • Treatment ... Management #Summary #rheumatology
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
- Arthritis Differential ... weeks) Can Be Caused ... #Differential # ... Diagnosis #MSK # ... rheumatology #Monoarticular
Top 10 situations when to think about lupus
1) Inflammatory joint pain (especially in the wrists and
Inflammatory joint pain ... fingers, or pain ... the face (many differential ... lupus #diagnosis #sle ... erythematosus #rheumatology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
10% of all lupus cases ... constitutional symptoms • Treatment ... Discontinuation of causal ... life-threatening • Treatment ... comparison #table #rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE ... autoantibodies that will cause ... Puncture, EEG Treatment ... Erythematosus #SLE ... CNS #neurology #rheumatology