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diagnosis hematology causes classification deficiency disease mcv anemias approach celiac dm2 elevatedmcv elevation false fe ferritin gastroenterology hgba1c incomplete increase
Causes of False Elevation and Reduction in HbA1c == False Elevation == Decreased RBC turnover • Iron, B-12,
and Reduction in HbA1c ... RBC turnover • Iron ... blood loss • Hemolytic ... anemia • Splenomegaly ... Diagnosis #DM2 #Differential
Hemolytic Anemias - Differential Diagnosis Algorithm Signs of anemia and hemolysis: • ↓ Haptoglobin • ↑ LDH
Hemolytic Anemias ... - Differential ... Diagnosis Algorithm ... Signs of anemia ... #Anemias #Differential
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Volume (MCV) - Differential ... Diagnosis Algorithm ... Decreased WBCs ... - Decreased/NormaI ... • Early Iron
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV Microcytic (MCV < 80) "TAILS": • Thalassemia
Algorithmic Approach ... to Anemia - Differential ... inflammation) • Iron ... , CKD • Hemolytic ... #MCV #Algorithm
Causes of Anemia with Low Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased Heme Synthesis or
Volume (MCV) - Differential ... Diagnosis Algorithm ... , serum iron decreased ... #elevatedMCV #Differential ... #Diagnosis #Algorithm
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
- Differential ... Diagnosis Algorithm ... MCH, MCHC, Serum Iron ... Reticulocytes • Iron ... #Diagnosis #Algorithm
Iron Deficiency Anemia - Differential Diagnosis Algorithm Labs: Ferritin, iron, transferrin, TIBC, TSAT, sTfR • Blood loss:
Anemia - Differential ... Diagnosis Algorithm ... extravascular) hemolysis ... #Deficiency #Anemia ... #Differential #
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... - Differential ... Diagnosis Algorithm ... without platelet decrease ... #Anemia #Differential
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Volume (MCV) - Differential ... Diagnosis Algorithm ... Volume (<80 fL) • Iron ... • Bleeding • Hemolysis ... #Diagnosis #Algorithm
Causes of Iron Deficiency - Differential Diagnosis Algorithm • Blood loss: GI (cancer, ulcer, IBD), GU
- Differential ... Diagnosis Algorithm ... Intravascular hemolysis ... MALABSORPTION • Decreased ... #Deficiency #Differential
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