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differential causes hemolytic rheumatology algorithm erythematosus lupus sle symptoms intravascular management vasculitis workup agglutinin anemias antibody arteritis autoantibodies autoimmune cold
Laboratory Testing in Hemolytic Anemia Intravascular vs Extravascular Hemolysis Reticulocytes Unconjugated bilirubin LDH Peripheral smear Haptoglobin Urine hemosiderin Urine hemoglobin Carboxyhemoglobin #Hemolytic #Anemia #Laboratory #Testing #workup
Anemia Intravascular ... vs Extravascular ... Hemolysis Reticulocytes ... Testing #workup #diagnosis ... #hematology #hemolysis
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
for Hemolysis - ... Hemolysis: • Mechanical ... Hemolysis: • ... EricsMedicalLectures/ #Hemolysis ... #hematology #anemia
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Hemolysis - Differential ... and RES-mediated hemolysis ... - Hemolysis within ... anemia • ... malformations #Hemolysis
Hemolytic Anemias - Differential Diagnosis Algorithm Signs of anemia and hemolysis: • ↓ Haptoglobin • ↑ LDH
Algorithm Signs ... of anemia and hemolysis ... Immune-mediated Hemolysis ... Nonimmune-mediated Hemolysis ... #hematology
Warm Antibody Autoimmune Hemolytic Anemia 1) DIAGNOSE AIHA • Anemia: macrocytic > normocytic, ↑ reticulocytes •
Anemia 1) DIAGNOSE ... reticulocytes • Hemolysis ... FOR a cause → Systematic ... #Anemia #diagnosis ... management #treatment #rheumatology
Iron Deficiency Anemia - Differential Diagnosis Algorithm Labs: Ferritin, iron, transferrin, TIBC, TSAT, sTfR • Blood loss:
Iron Deficiency Anemia ... - Differential Diagnosis ... (not extravascular ... ) hemolysis, Intensive ... Algorithm #ferritin #hematology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
- Differential Diagnosis ... • Bleeding • Hemolysis ... #MCV #Classification ... #Differential #Diagnosis ... Algorithm #Causes #Hematology
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
- Differential Diagnosis ... deficiency • Fanconi’s anemia ... Autoimmune Diseases: • Systemic ... Antibody-mediated hemolysis ... #Hematology
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
Differential Diagnosis ... for Hemolytic Anemia ... #Diagnosis #causes ... #classification ... #hematology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
hemorrhage and hemolysis ... hemolysis Platelet ... anemia Indirect ... the severity of hemolysis ... #Workup #Hematology
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