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diagnosis table allergy differential management causes classification pharmacology algorithm criticalcare indications signs types vasopressors acid acidosis acute airway anesthesia anesthesiology
Shock and Vasoactive Drugs 1) Determine type and etiology of shock • Distributive: Sepsis, Anaphylaxis, Neurogenic
Drugs 1) Determine ... Distributive: Sepsis, Anaphylaxis ... Understand vasoactive drug ... #Vasoactive #Drugs ... diagnosis #management #comparison
Angioedema - Classification Diagnosis and Treatment Types of Angioedema: • Acute allergic angioedema - Usually occurs with
Angioedema - Classification ... Acute allergic angioedema ... • Non-allergic drug ... urticaria • Hereditary ... angioedema - Rare
Stridor - Differential Diagnosis Framework: High-pitched, variable respiratory sound ETIOLOGIES: Infectious: • Retropharyngeal abscess • Acute epiglottitis • Peritonsillar
Allergic/Immune: • Anaphylaxis ... • Hereditary ... angioedema Congenital ... malformations • Anaphylaxis ... Tracheal stenosis • Anaphylaxis
Bedside Classification of Shock Hypovolemic shock - Vomiting, diarrhea, overdiuresis - Hemorrhage (GI, peritoneal, RP) Distributive shock
Classification of Shock ... Hypovolemic shock ... - Septic shock ... Adrenal crisis - Anaphylaxis ... #Cardiogenic #Comparison
Tranexamic Acid - Indications and Pharmacology Pharmacokinetics: • MOA: Inhibits plasminogen activation to plasmin & inhibits fibrinolysis
swelling in w/ hereditary ... angioedema) • ... Hypersensitivity & anaphylaxis
Cold Urticaria Prevalence - 0.05% in the population Disease onset - Mostly 2nd to 4th decades of life Causes
Drugs 5. ... Female predominance Anaphylaxis ... lesions - Wheals/angioedema ... , Hypotension, shock ... #rheumatology #comparison
Vasopressors and Inotropes • Norepinephrine - Levophed - "Levo" - Generally thought of as the first
pressor added in shock ... - ACLS (1st), Anaphylaxis ... in refractory shock ... in setting of shock ... criticalcare #summary #comparison
Manifestations of Anaphylaxis by Body System Dermatologic/mucosal - Eyes: periorbital swelling/erythema, injected conjunctiva, tears - Oral mucosa:
Manifestations of Anaphylaxis ... - Oral mucosa: angioedema ... piloerection, angioedema ... : bradycardia, shock ... Signs #Symptoms #Anaphylaxis
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 Shock - Differential Diagnosis Framework MAP = CO x SVR Hypovolemic (↓ Intravascular volume): • Hemorrhage, dehydration due
Shock - Differential ... Sepsis. neurogenic, anaphylaxis ... adrenal crisis, drugs ... uw_IMresidency #Shock ... Diagnosis #table #comparison
Causes of Angioedema: Differential Diagnosis Framework Mast-cell mediated: • IgE dependent allergic reactions: Food, Drugs, Latex, Stings
Causes of Angioedema ... reactions: Food, Drugs ... mediated: • ACEi • Hereditary ... inhibitor deficiency (hereditary ... angioedema) •
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