38 results
Workup of Hypercalcemia - Differential Diagnosis Algorithm
High or Normal PTH:
 • Hyperparathyroidism: Parathyroid adenoma, Parathyroid hyperplasia,
Workup of Hypercalcemia ... Hypocalciuric Hypercalcemia ... calcitriol induced hypercalcemia ... Infantile idiopathic hypercalcemia ... @aishaikh #Hypercalcemia
Causes of Hypercalcemia
Hypercalcemia due to increased bone Ca2+ resorption:
 • Primary hyperparathyroidism, Malignancy, Pseudohyperparathyroidism, Renal failure,
Causes of Hypercalcemia ... Hypercalcemia ... Immobilization Hypercalcemia ... hypocalciuria, Thiazides Hypercalcemia ... intoxication #Hypercalcemia
Pathophysiology of Tumor Lysis Syndrome (TLS)
Tumor Cell Lysis
-> Release of DNA
 • Purines -> Hypoxanthine /
of Tumor Lysis Syndrome ... (TLS) Tumor Cell ... -> Allantoin (High ... urine pH) • Hypocalcemia ... • Hyperkalemia
Hypercalcemia - Differential Diagnosis Algorithm
Elevated PTH (High or normal):
 • Primary Hyperparathyroidism
 • Familial Hypocalciuric Hypercalcemia
Low
Hypercalcemia - ... (High or normal ... Hypocalciuric Hypercalcemia ... Thiazides/Lithium #Hypercalcemia ... Algorithm #causes #endocrinology
Classification of Tumor Lysis Syndrome (TLS) and Treatment of Metabolic Abnormalities of TLS
Laboratory TLS:
 • Uric
(TLS) and Treatment ... other symptomatic hypocalcemia ... Treatment of TLS ... hydroxide • Hyperkalemia ... • Hypocalcemia
Multiple Endocrine Neoplasias (MEN syndromes) 

MEN I
• Hyperparathyroidism 
• Hypercalcemia 
• Possible ZE syndrome 
• Various
Hyperparathyroidism • Hypercalcemia ... Various Pituitary path ... Hyperparathyroidism • Hypercalcemia ... MultipleEndocrineNeoplasia #Differential ... #Endocrinology
Differential Diagnosis for ST Segment Elevations
 - ACUTE STEMI 
 - PULMONARY EMBOLISM 
 - LBBB
Differential Diagnosis ... BRUGADA SIGN (SYNDROME ... PERICARDITIS - HYPERKALEMIA ... REPOLARIZATION - HYPERCALCEMIA ... ANEURYSM - LVH (HIGH
Hypercalcemia Workup and Differential Diagnosis Framework
1) Determine whether PTH-dependent
2) Assess for other hormonal causes
3) Assess for
Hypercalcemia Workup ... and Differential ... Determine whether PTH-dependent ... uw_IMresidency #Hypercalcemia ... Diagnosis #algorithm #endocrinology
Hypercalcemia - Differential Diagnosis Algorithm
Primary Hyperparathyroidism
 • Adenoma
 • Hyperplasia
 • MEN 1 and 2A
Tertiary Hyperparathyroidism
Hypercalcemia - ... Hyperparathyroidism • Hypercalcemia ... Hypocalciuria Hypercalcemia ... Malignancy • PTH-Related ... Paget's Disease #Hypercalcemia
Hypocalcemia - Differential Diagnosis Algorithm - Low and High PTH
LOW PTH - Hypoparathyroid
 - Congenital (Pediatric)
Hypocalcemia - Differential ... Algorithm - Low and High ... Tumor lysis syndrome ... laxatives) #Hypocalcemia ... #endocrinology