27 results
diagnosis causes hematology rheumatology vasculitis pulmonary comparison radiology radiologyassistant algorithm consolidation ctchest hemolysis huv management microangiopathy pathophysiology thrombotic urticarial abdominal
Diagnosis and Management of Hypocomplementemic Urticarial Vasculitis (HUV) Diagnosis of HUV 1) Chronic urticaria 2) Leukocytoclastic vasculitis 3)
Management of Hypocomplementemic ... Urticarial Vasculitis (HUV ... Diagnosis of HUV ... vasculitis 3) Hypocomplementemia ... TerrierBen #Hypocomplementemic
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Causes of Hypocomplementemia ... A - Atypical HUS ... @AnnKumfer #Hypocomplementemia ... #Low #Complement ... Mnemonic #diagnosis #differential
Pathophysiology of Hypocomplementemic Urticarial Vasculitis C1q/anti-C1q antibiody -> Immune Complex Formation - Complement Pathway Activation (C3a and C5a)
Pathophysiology of Hypocomplementemic ... Complex Formation - Complement ... TerrierBen #Hypocomplementemic ... Urticarial #Vasculitis #HUV
Thrombotic Microangiopathies - Primary Thrombotic Microangiopathy (TMA) - Differential Diagnosis Table • Thrombotic Thrombocytopenic Purpura (TTP)
Microangiopathy (TMA) - Differential ... Diagnosis Table ... HUS (aHUS) ... - Complement-mediated ... TMA #hematology #differential
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Vasculitides - Differential ... often involved • Hypocomplementemic ... Urticaria and hypocomplementemia ... ear disease Differential ... against MPO • Complement
Pulmonary Renal Syndromes and Mimics - Differential Diagnosis Framework Diffuse alveolar hemorrhage + rapidly progressive glomerulonephritis 90%: -
Syndromes and Mimics - Differential ... anti-GBM) 10%: - Low Complement ... Vasculitis - Normal Complement ... hypertension - MAHA: HUS ... , atypical HUS,
Thrombotic Microangiopathy - TTP VS HUS Big picture points : Often hard to differentiate the two entities,
Microangiopathy - TTP VS HUS ... Often hard to differentiate ... entities, but has ... HemolyticUremicSyndrome #HUS ... Comparison #Diagnosis #Table
Effect of Selected Diseases on Complement Levels - C3, C4 • SLE C3 ↓ C4 ↓↓
Selected Diseases on Complement ... C3 ↓ C4 → • HUS ... ThePeanutKidney #Complement ... Levels #C3 #C4 #differential
Differential diagnosis of schistocytes / fragmentation hemolysis: • Thrombotic microangiopathies (TMA) - TTP
Differential diagnosis ... hemolytic-uremic syndrome (ST-HUS ... ) - Complement-mediated ... known as atypical HUS ... #schistocytes #differential
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
Glomerulonephritis (RPGN) RPGN has ... staining): • Low Complement ... Idiopathic • Normal Complement ... Glomerulonephritis #Vasculitis #differential
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