34 results
Hemolytic Anemias - Differential Diagnosis Algorithm

Signs of anemia and hemolysis:
 • ↓ Haptoglobin
 • ↑ LDH
Hemolytic Anemias ... - Differential ... • Extrinsic RBC ... #Anemias #Differential ... Diagnosis #Algorithm #hematology
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased WBCs
 - Decreased/NormaI
Volume (MCV) - Differential ... Bleed • Hemolysis ... Microangiopathic Hemolytic ... #Differential # ... Algorithm #Causes #Hematology
Red Blood Cell (RBC) Morphology Atlas
 • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Red Blood Cell (RBC ... ) Morphology Atlas ... Liver diseases, Bleeding ... key #diagnosis #differential ... #hematology
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
) Morphology Microcytic ... Microangiopathic Hemolytic ... Unstable hemoglobin disorders ... #Morphology #differential ... #diagnosis #hematology
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
- Differential ... Membrane Disorder ... Disorder - Acquired ... Classification #Approach #Differential ... Algorithm #Causes #Hematology
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... other reproducible morphologic ... membrane disorder ... #Anemia #Differential ... Algorithm #workup #hematology
Warm Antibody Autoimmune Hemolytic Anemia 
1) DIAGNOSE AIHA
 • Anemia: macrocytic > normocytic, ↑ reticulocytes
 •
AIHA • Anemia ... ↑ LDH • Anti-RBC ... • Blood smear: Differential ... #management #treatment ... #rheumatology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
anemia): ... lymphoproliferative disorders ... • Intrinsic RBC ... Extravascular #Causes #differential ... #diagnosis #hematology
Blood Disorders - Markers and Differential Diagnosis Algorithm 
Acute
 • Myloid (AML) - CD13, CD33, CD34,
- Markers and Differential ... - Abnormal morphology ... Pelger-Huet, Macrocytic anemia ... bcr-able (+) ↑ WBC ... #hematology #Markers
Approach to Leukocytosis - Differential Diagnosis Algorithm

Features of hematologic malignancy:
 • Symptoms: B-symptoms, bruising/bleeding, fatigue/weakness, immunosuppression
Leukocytosis - Differential ... Features of hematologic ... B-symptoms, bruising/bleeding ... hepatomegaly • Labs: anemia ... Diagnosis #Algorithm #hematology