901 results
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
• Direct renin inhibitor ... Renin release inhibition ... of aldosterone inhibition ... differential #diagnosis #pathophysiology
Pathophysiology of ACE inhibitor-induced angioedema: Angioedema is a vascular reaction associated with tissue (subcutaneous, submucosal) edema
Pathophysiology ... of ACE inhibitor-induced ... substances in ACE inhibitor-induced ... presence of ACE inhibition ... Bradykinin #ACE #Inhibitor
Signaling Mechanism of PD-1 and PD-L1 and Inhibition of PD-1 Signaling in Microsatellite-Instability–High Cancers. MHC1 denotes
and PD-L1 and Inhibition ... histocompatibility complex 1 #Pathophysiology ... Pharm #PD1 #PDL1 #Inhibition
Thiazide induced Hyponatremia - Pathophysiology
 • Reduced distal delivery
 • Inhibition of the NCC (dilution capcity)-
Hyponatremia - Pathophysiology ... distal delivery • Inhibition ... #Hyponatremia #Pathophysiology
Immune Reactions and Immunosuppressant Drugs

Glucocorticoids - Inhibition of cytokine synthesis, e.g., IL-1, IL-2
Muromonab-CD3 - Monoclonal antibody
Calcineurin
Glucocorticoids - Inhibition ... Calcineurin inhibitors - Inhibition ... #Pharmacology #Pathophysiology
NSAIDS and their effects on the Kidney - Pathophysiology

Arachidonic Acid metabolites into alternative pathways that modify
on the Kidney - Pathophysiology ... Prostaglandin inhibition ... HTN, Edema • Inhibition ... nephrology #Effects #pathophysiology
Renal Effect of NSAIDs Inhibition of Prostaglandin Synthesis

 - Renal disease, Cardiovascular disease -> Decreased renal
Effect of NSAIDs Inhibition ... #Pharmacology #Pathophysiology
Anticonvulsants as Mood Stabilizers: Mechanism and Side-effect
Examples: Valproate, Carbamazepine, Lamotrigine
 • Mild anticholinergic effect -> Drowsiness
bipolar disorder • Inhibition ... #SideEffects #Pathophysiology
Mixing Study
 • Clotting tests can be abnormal due to either a clotting factor deficiency, or
deficiency, or an inhibitor ... Patient has a factor inhibitor ... diagnosis #hematology #pathophysiology
The Inhibited Pathway caused by N2O, leading to a decrease in the active form of Vitamin
are due to its inhibition ... the irreversible inhibition ... #Pathophysiology