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diagnosis differential causes anemia injury liver thrombocytosis approach blood calculation classification coagulation comparison deficiencies disorders elevated fever hepatitis immunecompromised immunocompromised
Summary of Coagulation Deficiencies Inherited: • Hemophilia A - Deficiency of Factor VIII • Hemophilia B -
of Factor IX Acquired ... celiac disease, CF ... DIC - Septic shock ... Deficiencies #Summary #table ... comparison #diagnosis #hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Differential Diagnosis Algorithm ... Infectious: • Acute ... or Chronic Inflammatory ... malignancy • Iron deficiency ... #Causes #Hematology
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
Differential Diagnosis Algorithm ... Blood Loss • Acute ... RBCs on Smear • Chronic ... Metabolism Disorder - Acquired ... #Causes #Hematology
Diagnostic Framework for Anemia (Morphological Approach - MCV) Low MCV - <80fL - "Microcytic" • Iron deficiency
• Anemia of chronic ... kidney disease, Acute ... patients), "Hospital-acquired ... , Folate deficiency ... diagnosis #causes #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Differential Diagnosis Algorithm ... → Refer to hematology ... , deficiency anemia ... • Infections: Chronic ... #hematology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor The maturation factor is
deficiencies: Iron deficiency ... • "Hospital-acquired ... Index > 3: • Acute ... cell anemia, G6PD deficiency ... Production #Index #hematology
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Causes of Acute ... Autoimmune hepatitis, Acute ... Budd-Chiari, Congestion/CHF ... Hepatic Artery: Shock ... #algorithm #hepatology
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Differential Diagnosis Algorithm ... RA, SLE, PRV, Chronic ... Normal RBCs • Acute ... • Early Iron Deficiency ... #Causes #Hematology
Non-ACS Myocardial Injury - Elevated Troponin Differential Diagnosis and Workup Algorithm • Chronic Myocardial Injury: End
• Chronic Myocardial ... (ie Sarcoid), Chronic ... Pre-Coronarv): Shock ... Tachycardia-induced HF ... Occlusion • Stable
Blood Disorders - Markers and Differential Diagnosis Algorithm Acute • Myloid (AML) - CD13, CD33, CD34,
Differential Diagnosis Algorithm ... Acute • Myloid ... T-cell - CD7, CD3 Chronic ... Blood #Disorders #hematology ... Differential #Diagnosis #Algorithm
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