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management hematology differential oncology algorithm classification infectiousdiseases pulmonary aplastic autoimmune disease hemophagocytic hiv hlh infections leukemia lung lymphohistiocytosis mds myelodysplastic
Budd Chiari Syndrome Hepatic vein obstruction. Can be caused by thrombosis or sometimes a tumour. Can lead
Budd Chiari Syndrome ... Can be caused by ... Can lead to shock ... #Diagnosis #Causes ... #Signs #Symptoms
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Illness Script Signs ... and symptoms: ... Diagnosis: • Pancytopenia ... Treatment: • Consider ... #treatment #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... old, ~10,000 new cases ... cytopenias (usually anemia ... #Management #treatment ... #hematology #oncology
Streptococcal Toxic Shock Syndrome (STSS) Complication of invasive GAS disease characterized by shock & MOF → occurs
Syndrome (STSS) ... GAS in 30% of cases ... kidneys, liver, lung/ARDS ... #Syndrome #STSS ... #diagnosis
Suspected Celiac Disease - Diagnosis Algorithm Celiac disease suspected: • Signs and symptoms of celiac disease •
suspected: • Signs ... and symptoms of ... Iron-deficiency anemia ... unresponsive to treatment ... without discernable cause
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... Dehydration • Symptoms ... WBC >100k, + lab signs ... #TLS #diagnosis ... #management #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
and petechiae Causes ... Treatment: ... • Improve the symptoms ... #oncology #hematology ... #diagnosis #management
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
glucocorticoid treatment ... organ-specific signs ... or symptoms (eg ... #Differential #diagnosis ... #hematology #eosinophilia
Autoimmune Myositis Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
less systemic symptoms ... , holster sign, ... anti-synthetase syndrome ... after 2 years of treatment ... #rheumatology
Biphasic Illness of Leptospirosis Some patients do not progress to severe disease. Others, rapidly develop severe disease
brief interval symptom ... hemorrhage • ARDS ... • Shock and multi-organ ... Biphasic #Phases #Diagnosis ... #Illness #Signs
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