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diagnosis liver algorithm injury causes hepatitis abnormal acute biliary bilirubinemia chemistry cholangitis cirrhosis dili drug elevated elevation enzymes functiontest gastroenterology
Evaluation abnormal liver tests in pregnancy - Cholestatic Pattern - Hepatocellular Pattern #LFTs #transaminits #pregnancy #obgyn #obstetrics #hepatology #diagnosis
in pregnancy - Cholestatic ... Pattern - Hepatocellular ... Pattern #LFTs ... #transaminits #pregnancy ... obgyn #obstetrics #hepatology
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury Hepatocellular Liver Injury • AST/ALT elevation
Liver Enzymes (LFTs ... Liver #Enzymes #LFTs ... #Cholestatic #Transaminitis ... #diagnosis #differential ... #hepatology
Liver Function Test (LFTs) Elevation AST - Cardiac and skeletal muscle, kidney, brain ALT - More specific for
Function Test (LFTs ... ALT ≥ 3x ULN Cholestatic ... #FunctionTest #LFTs ... #Elevation #Transaminitis ... #diagnosis #hepatology
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis Hepatocellular Pattern (ALT or AST > ALP):
Function Tests - Differential ... Hepatocellular ... Alcoholic Hep, Drugs, Infection ... Burak @kwburak #LFTs ... Algorithm #diagnosis #hepatology
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
phosphatase) 2) Cholestatic ... Diagnosis: • Infections ... #Diagnosis #hepatology ... #algorithm #Transaminitis ... #LFTs #hepatitis
Jaundice - Differential Diagnosis Algorithm Pre-Hepatic - Unconjugated Hyperbilirubinemia Increased Production • Hemolysis • Ineffective Erythropoiesis • Hematoma Decreased
Jaundice - Differential ... Hyperbilirubinemia • Hepatocellular ... • Cholestatic ... #Differential # ... Algorithm #Causes #Hepatology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Interpretation of LFTs ... disease: > 2 • NASH ... chemistry #diagnosis #differential ... #Hepatology #transaminitis ... #LFTs #RValue #
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
10-20x normal - Infection ... normal - Hemolysis, NASH ... Liver #Injury #hepatology ... #LFTs #transaminitis ... #differential #
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Liver Injury - Differential ... Diagnosis Hepatocellular ... Parenchyma • Infectious ... Hepatitis, TB Cholestatic ... Acute #algorithm #hepatology
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Chronic - ongoing ↑ LFTs ... Calculate R-Value • Hepatocellular ... Mixed DILI • Cholestatic ... Idiosyncratic #differential ... gastroenterology #hepatology
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