68 results
Von Willebrand Disease - Most common inherited bleeding disorder 
Clinical 
 • Easy bruising 
 •
Von Willebrand Disease ... prolonged if very low ... factor VIII) Treatment ... VonWillebrand #Disease ... #Diagnosis #Hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Causes of Thrombocytosis ... disorders • Celiac disease ... effect following treatment ... Diagnosis #Algorithm #Causes ... #Hematology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Low Mean Corpuscular Volume (<80
Causes of Anemia ... Diagnosis Algorithm Low ... Renal Disease, Liver ... Diagnosis #Algorithm #Causes ... #Hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Causes of Anemia ... Neutrophils - Low ... Pregnancy) - Low ... Pernicious Anemia - Low ... #Hematology
Causes of Hypocomplementemia - CHAMPS Mnemonic
C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis
H - Heavy Chain deposition
Causes of Hypocomplementemia ... Chain deposition disease ... Hypocomplementemia #Low ... #differential #hematology
Thromboelastography (TEG) Based Management
 - If R time prolonged -> FFP 
 - If MA low
FFP - If MA low ... TEG #Management #treatment ... #diagnosis #hematology
Thromboelastography (TEG) based therapy and Management

If r time prolonged -> FFP
If MA low -> plts/cryoprecipitate (if
-> FFP If MA low ... Management #Diagnosis #Hematology ... Thromboelastogram #Treatment
Mechanisms Driving Increased Thrombosis and Bleeding in Liver Disease
Increased Thrombosis 
Increased Platelet-Vesset Wall Interaction 
 •
Bleeding in Liver Disease ... • Decr TFPI Low ... Clot #Cirrhosis #Pathophysiology ... #Hepatology #Liver
Causes of Polycythemia (Erythrocytosis) - Differential Diagnosis Algorithm
Relative - Normal RBC Mass / Decreased Plasma Volume
Causes of Polycythemia ... JAK-2 Positive - Low ... Cyanotic Heart Disease ... Diagnosis #Algorithm #Causes ... #Hematology
Diagnostic Framework for Anemia (Morphological Approach - MCV)
Low MCV - <80fL - "Microcytic"
 • Iron deficiency
Approach - MCV) Low ... chronic kidney disease ... Alcohol use, Liver disease ... differential #diagnosis #causes ... #hematology