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diagnosis differential hematology management algorithm anemia syndrome classification nutrition gastroenterology hyperkalemia iron oncology high pathophysiology potassium bleeding cirrhosis coagulation disease
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Causes of Thrombocytosis ... effect following treatment ... malignancy • Iron deficiency ... Diagnosis #Algorithm #Causes ... #Hematology
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Causes of Thrombocytosis ... a.k.a Reactive Thrombocytosis ... specifically: iron deficiency ... Differential #Diagnosis #Causes ... #hematology #secondary
Thrombocytosis - Differential Diagnosis Platelet Count > 450 Reactive: • Anemia/blood loss (Fe deficiency) • Infection/Sepsis • Non-infectious
Thrombocytosis - ... blood loss (Fe deficiency ... BrighamChiefs #Thrombocytosis ... Differential #Diagnosis #causes ... #Platelets #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Approach to Thrombocytosis ... → Refer to hematology ... Consider reactive thrombocytosis ... Acute hemolysis, deficiency ... Rebound effect from treatment
Iron Deficiency Anemia - Differential Diagnosis Algorithm Labs: Ferritin, iron, transferrin, TIBC, TSAT, sTfR • Blood loss:
Iron Deficiency ... Zinc excess or deficiency ... , Copper deficiency ... Anorexia, Pregnancy, Lactation ... Algorithm #ferritin #hematology
Causes of Splenomegaly - Differential Diagnosis Algorithm Infectious • Bacterial • Viral (EBV) • Parasitic • Fungal Congestive
Causes of Splenomegaly ... vera, essential thrombocytosis ... Spherocytosis • Acquired causes ... Diagnosis #Algorithm #Causes ... #Hematology
Hyperviscosity Syndrome - Causes and Treatment - Waldenstrom macroglobulinemia (most common) / Plasmapheresis - Multiple
Hyperviscosity Syndrome - Causes ... and Treatment ... Hydroxyurea - Thrombocytosis ... Hyperviscosity #Syndrome #Causes ... Differential #Diagnosis #Treatment
Causes of Severe Acute Liver Injury - Ichemic hepatitis - Acute biliary obstruction - Drug-Induced liver
Causes of Severe ... -1 antitrypsin deficiency ... Severe #Acute #Causes ... #Differential #Hepatology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Causes of Thrombocytopenia ... Megakaryopoiesis • B12 Deficiency ... • Folate Deficiency ... Diagnosis #Algorithm #Causes ... #Hematology
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Causes of Bleeding ... • Factor VIII Deficiency ... • Factor IX Deficiency ... Diagnosis #Algorithm #Causes ... #Hematology
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