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differential management oncology algorithm syndrome neurology rheumatology workup anemia blood comparison disorders hemeonc reactions chronic classification clinical cll diffuse hemophagocytic
Causes of Neutrophilia - Increased Neutrophils - Differential Diagnosis Algorithm Infection • Bacterial • Abscess • Viral Medications
Causes of Neutrophilia ... - Differential Diagnosis ... pancytopenia, blast cells ... #Algorithm #Causes ... #Hematology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Causes of Diffuse ... - Differential Diagnosis ... Reed-Sternberg Cells ... #Algorithm #Causes ... #Hematology #Oncology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Causes of Thrombocytosis ... - Differential Diagnosis ... Chronic Myelogenous Leukemia ... effect following treatment ... #Hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
= funny-shaped cells ... old, ~10,000 new cases ... transformation to acute leukemia ... #Management #treatment ... #hematology #oncology
Approach to Leukocytosis - Differential Diagnosis Algorithm Features of hematologic malignancy: • Symptoms: B-symptoms, bruising/bleeding, fatigue/weakness, immunosuppression
- Differential Diagnosis ... Features of hematologic ... predominant immature cells ... #Algorithm #hematology ... #WBC #Leukemoid
Basophilia - Differential Diagnosis Framework Basophils < 1% of the total white blood cell count Basophils function similarly
- Differential Diagnosis ... similarly to mast cells ... Chickenpox Other Causes ... #Differential #Diagnosis ... #causes #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Rapidly rising blast cells ... : Granulocytic cells ... organs When Cancer Cells ... #Hematology #Oncology ... #Diagnosis
Erythroderma - Diagnostic Algorithm. Pathophysiology: 1) Extensive cutaneous capillary dilation, results in widespread exfoliation of the
Erythroderma - Diagnostic ... germinative skin cells ... Causes: 1) Exfoliative ... Skin-homing T-cells ... Dermatology #Rash
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Skin: - CLL cells ... smear: Smudge cells ... or basket cells ... microglobulin Treatment ... #oncology #hematology
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophilia, 500-1,500 cells ... Hypereosinophilia, >1,500 cells ... glucocorticoid treatment ... #Differential #diagnosis ... #hematology #eosinophilia
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