19 results
Erythroderma - Diagnostic Algorithm. Pathophysiology: 1) Extensive cutaneous capillary dilation, results in widespread exfoliation of the
Pathophysiology: ... Causes: 1) Exfoliative ... Skin-homing T-cells ... Nikolsky #Algorithm #Differential ... #Ddxof
Drug-Induced Edema
Drug-induced edema is caused by many drugs & can coincide with or worsen pre-existing peripheral
is caused by many ... release from mast cells ... #Medication #Causes ... #Differential # ... Pharmacology #Pathophysiology
Uncommon Causes of Noncardiogenic Pulmonary Edema (NCPE) - Differential Diagnosis Framework

High Altitude Pulmonary Edema:
 • Accumulation
(NCPE) - Differential ... some red blood cells ... : • Pathophysiology ... • Pathophysiology ... #causes #differential
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Disease, PRES Pathophysiology ... autoantibodies that will cause ... Erythematosus #SLE #CNS #neurology ... #rheumatology # ... cerebritis #diagnosis #management
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
ATRA treatment Pathophysiology ... Release from blast cells ... myalgias, HoTN, edema ... initiation • Differential ... APML #diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... Activation of CD8 T cells ... Drugs, Unknown cause ... Lymphohistiocytosis #diagnosis #management ... treatment #summary #rheumatology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
Etiology: • Pathophysiology ... Reversible course Differential ... the underlying cause ... Syndrome #diagnosis #management ... #neurology
Intracranial Hemorrhage (ICH) and Increased Intracranial Pressure (ICP) - Pathophysiology
ICH Management:
1. Manage Blood Pressure
  •
Pressure (ICP) - Pathophysiology ... ICH Management ... = dilated BV = raises ... water leaves brain cells ... #management
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... Lysis of tumor cells ... TLS #diagnosis #management ... #hematology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
protein C and S Pathophysiology ... Schistocytes, helmet cells ... Treat primary cause ... #treatment #management ... #hematology