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nephrology differential treatment algorithm infectiousdiseases acute hematology syndrome urine aki clinical hematuria microbiology urology workup injury oncology renal syndromes barre
Atlas of Urine Microscopy Findings • Epithelial cells - Normal • Renal tubular cells - Acute
• Red cell casts ... • White cell casts ... infection • Hyaline casts ... disease • Granular casts ... #nephrology #casts
Urine Microscopy - Casts Acellular Casts • Hyaline Casts - Consists of only precipitated Tamm-Horsfell protein without
Urine Microscopy ... - Casts Acellular ... #Urine #Microscopy ... #nephrology #interpretation ... #diagnosis
Hematuria Workup and Diagnosis Algorithm • Confirm hematuria → Urinalysis >3 RBCs/HPF, exclude mimics, repeat testing
Hematuria Workup and Diagnosis ... → Urine culture ... proteinuria, RBC casts ... if cause not identified ... uw_IMresidency #Hematuria #Diagnosis
Acute Kidney Injury - Differential Diagnosis Framework PRERENAL: - Intrarenal vasoconstriction-hemodynamically mediated - Systemic vasodilation - Volume
Glomerular (red blood cells ... white blood cell casts ... renal tubular cell casts ... or pigmented casts ... treating underlying cause
Simplified Approach to Acute Kidney Injury (AKI) 1) IS THIS AN EMERGENCY? Is there a dialysis indication
PROBLEM ~80% of AKI cases ... are caused by prerenal ... you confirmed diagnosis ... Assess UA w/ microscopy ... for WBCs, RBCs, casts
Hematuria - Differential Diagnosis Framework Gross Hematuria: Red/Dark urine • 1ml blood/liter urine can induce color change
- Differential Diagnosis ... hematuria: - RBC casts ... → Diagnostic of ... #Differential #Diagnosis ... #causes #urology
Urinary Casts and Disease Associations Hyaline - May be nonspecific; seen in normal individuals or during severe
Urinary Casts and ... breakdown of cellular casts ... heme-granular casts ... 34t5DgJ #Urinary #Casts ... #Diagnosis #Nephrology
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis Baseline Investigations: full blood count with differential,
and Differential Diagnosis ... dipstick, urine microscopy ... osmolarity If cause ... , urine culture, ... #nephrology #causes
Urine Microscopy Instructions 1) Spin fresh urine sample (10-15mL) in a centrifuge for 3-5 minutes - Don't
Urine Microscopy ... one drop on a microscope ... under lower power (casts ... #Instructions #nephrology ... #diagnosis
Algorithmic Approach to Acute Interstitial Nephritis When to suspect AIN? (not sensitive) • AKI, AKD, rapidly progressive
sterile pyuria, WBC casts ... eosinophiluria, microscopic ... proteinuria, granular casts ... AIN #Algorithm #nephrology ... #diagnosis
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