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hematology differential oncology causes disorders management mds thrombocytosis aplastic atlas blood cancer chronic classification cll elevatedmcv key leukemia lymphocytic lymphomas
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic ... = funny-shaped cells ... cytopenias (usually anemia ... transformation to acute ... #hematology #oncology
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Liver diseases, Myelodysplastic ... • Sickle cells ... Malignant tumors, Acute ... Morphology #Atlas #key #diagnosis ... #differential #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
factor (GCSF) treatments ... marrow studies Treatment ... Immunosuppressive treatment ... #Syndromes #diagnosis ... #hematology #oncology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
- Differential Diagnosis ... Algorithm Normal ... Dysplastic • Myelodysplastic ... Macrocytosis, Target Cells ... #Hematology
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
- Differential Diagnosis ... Algorithm Decreased ... Normal RBCs • Acute ... #Algorithm #Causes ... #Hematology
Blood Disorders - Markers and Differential Diagnosis Algorithm Acute • Myloid (AML) - CD13, CD33, CD34,
Algorithm Acute ... Disorders - Myelodysplastic ... Pelger-Huet, Macrocytic anemia ... or λ), Smudge Cells ... #Algorithm
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Algorithm Spurious ... Infectious: • Acute ... effect following treatment ... Iron deficiency anemia ... #Hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
- Differential Diagnosis ... Algorithm Peripheral ... hemolysis, deficiency anemia ... Rebound effect from treatment ... #Algorithm #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... • Hypocellular myelodysplastic ... Treatment: ... #oncology #hematology ... #diagnosis #management
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
- Differential Diagnosis ... Algorithm Hodgkin ... Responsive to Treatment ... Treated Like Acute ... #Diagnosis #NonHodgkin
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