35 results
Hemolytic Anemias - Differential Diagnosis Algorithm

Signs of anemia and hemolysis:
 • ↓ Haptoglobin
 • ↑ LDH
Hemolytic Anemias ... - Differential Diagnosis ... Abnormal peripheral smear ... #Diagnosis #Algorithm ... #hematology
Laboratory Testing in Hemolytic Anemia

Intravascular vs Extravascular Hemolysis
Reticulocytes
Unconjugated bilirubin
LDH
Peripheral smear
Haptoglobin
Urine hemosiderin
Urine hemoglobin
Carboxyhemoglobin

#Hemolytic #Anemia #Laboratory #Testing #workup
Anemia Intravascular ... LDH Peripheral smear ... #Anemia #Laboratory ... Testing #workup #diagnosis ... #hematology #hemolysis
Peripheral Blood Smear Analysis
Hypochromia
Megaloblastic Anemia
Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS)
Microspherocytes: Autoimmune hemolytic anemia
Sickled red
Peripheral Blood Smear ... Microangiopathic hemolytic ... Microspherocytes: Autoimmune hemolytic ... Peripheral #Blood #Smear ... #Analysis #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm
Hereditary:
 • Peripheral blood smear + DAT + further History
 •
Hemolytic Anemia ... - Differential Diagnosis ... Peripheral blood smear ... History • Bite cells ... #Diagnosis #Algorithm
Warm Antibody Autoimmune Hemolytic Anemia 
1) DIAGNOSE AIHA
 • Anemia: macrocytic > normocytic, ↑ reticulocytes
 •
Anemia 1) DIAGNOSE ... AIHA • Anemia ... C3d • Blood smear ... #Anemia #diagnosis ... #management #treatment
Peripheral blood findings in microangiopathic hemolytic anemia.  DIC is a clinical and laboratory diagnosis, not
and laboratory diagnosis ... polychromatophilic cells ... arrow) Peripheral smear ... #anemia #Hematology ... #Pathology #Smear
Autoimmune Hemolytic Anemia (AIHA) Pathophysiology - Warm vs Cold AIHA
Warm AIHA:
 - 70%; IgG mediated
 -
Autoimmune Hemolytic ... Anemia (AIHA) Pathophysiology ... or negative - Smear ... C3 positive - Smear ... #diagnosis #hematology
Warm vs Cold Autoimmune Hemolytic Anemia
Warm Autoimmune Hemolytic Anemia:
 • Mechanism: IgG and Complement-mediated
 • Etiology:
Hemolytic Anemia ... Spherocytes • Treatment ... • Treatment: Warm ... #Anemia #hematology ... #diagnosis #comparison
Dacrocytes (tear drop cells) 
Other poikilocytes resemble a pear or teardrop. The narrow, tapered end
may be
Dacrocytes (tear drop cells ... each of the above photos ... thalassemia, and some hemolytic ... anemias. ... BloodSmear #Blood #Smear
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased WBCs
 - Decreased/NormaI
- Differential Diagnosis ... Bleed • Hemolysis ... Microangiopathic Hemolytic ... #Differential #Diagnosis ... Algorithm #Causes #Hematology