12 results
Multiple Myeloma Diagnosis and Management Summary
Clinical Signs:
 • hyperCalcemia 28% (bone demineralization)
 • Renal disease 48%
Multiple Myeloma ... osteolytic lesions and pathologic ... marrow plasma cells ... #Multiple #Myeloma ... #oncology
Cutaneous manifestations associated with myelodysplastic syndrome
 • Myeloid hemopathy with the most frequent skin lesions (20%)
myelodysplastic syndrome • Myeloid ... hemopathy with ... #differential #diagnosis ... #dermatology #oncology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Syndrome (MD) - Diagnosis ... Management Summary myelo ... = funny-shaped cells ... 10,000 new cases diagnosed ... treatment #hematology #oncology
T-LGL leukemia - T-CeIl Large Granular Lymphocytic Leukemia
Clinical
 - Persistent (>6mo) lymphocytosis (2-20k) with proven clonality
required for dx - T-cells ... chronic LPD of NK cells ... are NK cells (sCD3 ... Lymphocytic #Leukemia #hemepath ... #pathology #diagnosis
Castleman's Disease and Associated Syndromes
HYALINE VASCULAR VARIANT
 • unicentric, HHV8-ve, children and young.
 • Hyalinized vessels
Diffuse plasma cells ... cell disorders (myeloma ... Disease #Variants #Diagnosis ... #Pathology
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework

Hematologic disorder characterized by the presence of either
to IgM multiple myeloma ... marrow plasma cells ... to light-chain myeloma ... Significance #hematology #diagnosis ... #oncology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
CML (Chronic Myeloid ... • Neutrophils (myeloid ... AML (Acute Myeloid ... Leukemia #Hematology #Oncology ... #Diagnosis
Indolent T-Lymphoblastic Proliferation (iT-LBP)
Features of iT-LBP:
 - May be seen in association with other malignancies (e.g.
Groups of TdT+ T-cells ... Proliferation #Hemepath ... #pathology #Clinical ... #diagnosis
Adult T-cell Leukemia / Lymphoma (ATLL) - Mimicking Angioimmunoblastic T-cell lymphoma with Hodgkin like cells

Features ATLL:
with Hodgkin like cells ... Leukemia #Lymphoma #Hemepath ... #pathology #Clinical ... #diagnosis
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
caused by blood cells ... , or all three myeloid ... , and the cells ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology