241 results
Pathophysiology of Hypocomplementemic Urticarial Vasculitis

C1q/anti-C1q antibiody ->
Immune Complex Formation - Complement Pathway Activation (C3a and C5a)
Pathophysiology ... Cytokines, Mast Cells ... Formation -> Vasculitis ... #HUV #Pathophysiology ... #Rheumatology
Approach to Leukocytosis - Differential Diagnosis Algorithm

Features of hematologic malignancy:
 • Symptoms: B-symptoms, bruising/bleeding, fatigue/weakness, immunosuppression
Leukocytosis - Differential ... Features of hematologic ... malignancy: • Symptoms ... : B-symptoms, bruising ... predominant immature cells
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... • Secondary Causes ... Vasculopathy #Purpura #Differential ... #Diagnosis #hematology ... #rheumatology #
Giant Cell (Temporal) Arteritis: Pathogenesis and investigations
Risk Factors:
 - Unclear environmental triggers (may be viral, not
old; F>M Signs/Symptoms ... Anemia - Giant cells ... palpation - Vasculitic ... Temporal #Arteritis #Pathophysiology ... #Vasculitis
Dermatological semiology of Cutaneous Vasculitis 

Clinicopathologic correlations
 • Purpura, papules, pustules, necrosis: involvement of small vessels
semiology of Cutaneous Vasculitis ... Identification of causes ... #dermpath #dermatology ... lesions #diagnosis #clinical ... pathology #lesions #differential
Bell's Palsy
Bell’s Palsy is a damage, acute weakness, or paralysis of the Facial nerve (7th CN),
Bell's Palsy Bell ... an identifiable cause ... The cause is unknown ... but its clinically ... neurology #anatomy #pathophysiology
Petechiae/Purpura - Diagnostic Algorithm. Pathophysiology: 1) Represent the passage of erythrocytes from the intravascular to extravascular
Pathophysiology: ... trauma, infection, vasculitis ... process such as vasculiitis ... #Diagnosis #Dermatology ... Palpable #Algorithm #Differential
Vascular Skin Lesions - Differential Diagnosis Algorithm
 - Petechiae < 0.2 cm diameter
 - Purpura 0.2
Skin Lesions - Differential ... #Vascular #Vasculitis ... #SkinRash #dermatology ... #Differential # ... Diagnosis #Algorithm #causes
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
Causes of Thrombocytopenia ... - Differential ... HUS • DIC • Vasculitis ... Diagnosis #Algorithm #Causes ... #Hematology
Dyspnea - Differential Diagnosis Framework

Cardiovascular Causes of Dyspnea:
 • Myocardium:
	- Heart failure
	- CAD/ACS
	- Valvulopathy
 • Electrical:
	-
Dyspnea - Differential ... Cardiovascular Causes ... Pulmonary HTN - Vasculitis ... Transverse myelitis • Hematology ... #dyspnea #sob #differential