41 results
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Joint Pain Rash ... infection Malar rash ... Seborrhea • Dermatomyositis ... Heliotrope • Dermatomyositis ... differential #diagnosis #rheumatology
Heliotrope Rash in Dermatomyositis

Peri-orbital edema and the heliotrope rash that we are all familiar with. Eyelid
Heliotrope Rash ... in Dermatomyositis ... #Dermatomyositis ... #Dermatology #Clinical ... #Photo #Face
Autoimmune Myositis
Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
Dermatomyositis ... can present with rash ... including heliotrope rash ... Myositis #diagnosis #rheumatology
Pathophysiology of Hypocomplementemic Urticarial Vasculitis

C1q/anti-C1q antibiody ->
Immune Complex Formation - Complement Pathway Activation (C3a and C5a)
Pathophysiology ... Cytokines, Mast Cells ... perivascular inflammatory cells ... Vasculitis #HUV #Pathophysiology ... #Rheumatology
ANTI-MDA5 DERMATOMYOSITIS

Cutaneous manifestations:
• Periorbital heliotrope (blue-purple) rash with edema
• Erythematous rash on the face, or the
ANTI-MDA5 DERMATOMYOSITIS ... (blue-purple) rash ... • Erythematous rash ... #rheumatology # ... dermatology #diagnosis
Erythroderma - Diagnostic Algorithm. Pathophysiology: 1) Extensive cutaneous capillary dilation, results in widespread exfoliation of the
Pathophysiology: ... germinative skin cells ... Skin-homing T-cells ... #Diagnosis #Dermatology ... #Rash #Erythroderma
Typical palpable purpura of Henoch Schönlein Purpura

#Henoch #Schonlein #Purpura #HSP #Skin #Rash #Clinical #Photo #Palpable #Dermatology
Schonlein #Purpura #HSP ... #Skin #Rash #Clinical ... #Photo #Palpable ... #Dermatology
Dermatomyositis (DM) and Polymyositis (PM): Pathogenesis and clinical findings
Elevated Antinuclear Antibodies: Anti-Jo-1, Anti-OJ, Anti-Mi2, Anti-SRP, Anti-EJ,
Dermatomyositis ... -> Heliotrope Rash ... primarily deltoids and hip ... flexors affected #Dermatomyositis ... PM #Diagnosis #Pathophysiology
Myositis and Myopathies
Polymyositis 
 • Progressive, symmetric muscle weakness 
 • Elevated CK, +Anti-Jo, +Anti-Mi2
Dermatomyositis
Anti-Jo, +Anti-Mi2 Dermatomyositis ... muscle weakness, rash ... diagnosis #comparison #rheumatology
Adult Onset Still's Disease - Yamaguchi Criteria
Major criteria:
 - Fever >= 39C lasting >= 1 weeks
- Typical skin rash ... non-pruritic, salmon-pink rash ... Leukocytosis >= 10,000 cells ... #Major #Minor #Rheumatology